Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical Resection
Plexiform neurofibromas are benign tumors originating from subcutaneous or visceral peripheral nerves, which are usually associated with neurofibromatosis type 1. Giant neurofibromas are very difficult to manage surgically as they are extensively infiltrative and highly vascularized. These types of...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/987623 |
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| author | Roberto Vélez Sergi Barrera-Ochoa David Barastegui Mercedes Pérez-Lafuente Cleofe Romagosa Manuel Pérez |
| author_facet | Roberto Vélez Sergi Barrera-Ochoa David Barastegui Mercedes Pérez-Lafuente Cleofe Romagosa Manuel Pérez |
| author_sort | Roberto Vélez |
| collection | DOAJ |
| description | Plexiform neurofibromas are benign tumors originating from subcutaneous or visceral peripheral nerves, which are usually associated with neurofibromatosis type 1. Giant neurofibromas are very difficult to manage surgically as they are extensively infiltrative and highly vascularized. These types of lesions require complex preoperative and postoperative management strategies. This case report describes a 22-year-old female with a giant plexiform neurofibroma of the lower back and buttock who underwent pre-operative embolization and intraoperative use of a linear cutting stapler system to assist with haemostasis during the surgical resection. Minimal blood transfusion was required and the patient made a good recovery. This case describes how a multidisciplinary management of these large and challenging lesions is technically feasible and appears to be beneficial in reducing perioperative blood loss and morbidity. Giant neurofibroma is a poorly defined term used to describe a neurofibroma that has grown to a significant but undefined size. Through a literature review, we propose that the term “giant neurofibroma” be used for referring to those neurofibromas weighing 20% or more of the patient's total corporal weight. |
| format | Article |
| id | doaj-art-1a870458c9964676ac41765bc7c1f488 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-1a870458c9964676ac41765bc7c1f4882025-02-03T06:11:33ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/987623987623Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical ResectionRoberto Vélez0Sergi Barrera-Ochoa1David Barastegui2Mercedes Pérez-Lafuente3Cleofe Romagosa4Manuel Pérez5Orthopaedic Oncology Unit, Orthopaedic Surgery and Traumatology Department, Hospital Universitari Vall d'Hebron, Pg Vall d'Hebron 129-139, 08035 Barcelona, SpainOrthopaedic Surgery and Traumatology Department, Hospital Universitari Vall d'Hebron, Pg Vall d'Hebron 129-139, 08035 Barcelona, SpainOrthopaedic Surgery and Traumatology Department, Hospital Universitari Vall d'Hebron, Pg Vall d'Hebron 129-139, 08035 Barcelona, SpainInterventional Radiology Service, Radiology Department, Hospital Universitari Vall d'Hebron, Pg Vall d'Hebron 129-139, 08035 Barcelona, SpainPathology Department, Hospital Universitari Vall d'Hebron, Pg Vall d'Hebron 129-139, 08035 Barcelona, SpainOrthopaedic Oncology Unit, Orthopaedic Surgery and Traumatology Department, Hospital Universitari Vall d'Hebron, Pg Vall d'Hebron 129-139, 08035 Barcelona, SpainPlexiform neurofibromas are benign tumors originating from subcutaneous or visceral peripheral nerves, which are usually associated with neurofibromatosis type 1. Giant neurofibromas are very difficult to manage surgically as they are extensively infiltrative and highly vascularized. These types of lesions require complex preoperative and postoperative management strategies. This case report describes a 22-year-old female with a giant plexiform neurofibroma of the lower back and buttock who underwent pre-operative embolization and intraoperative use of a linear cutting stapler system to assist with haemostasis during the surgical resection. Minimal blood transfusion was required and the patient made a good recovery. This case describes how a multidisciplinary management of these large and challenging lesions is technically feasible and appears to be beneficial in reducing perioperative blood loss and morbidity. Giant neurofibroma is a poorly defined term used to describe a neurofibroma that has grown to a significant but undefined size. Through a literature review, we propose that the term “giant neurofibroma” be used for referring to those neurofibromas weighing 20% or more of the patient's total corporal weight.http://dx.doi.org/10.1155/2013/987623 |
| spellingShingle | Roberto Vélez Sergi Barrera-Ochoa David Barastegui Mercedes Pérez-Lafuente Cleofe Romagosa Manuel Pérez Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical Resection Case Reports in Neurological Medicine |
| title | Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical Resection |
| title_full | Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical Resection |
| title_fullStr | Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical Resection |
| title_full_unstemmed | Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical Resection |
| title_short | Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical Resection |
| title_sort | multidisciplinary management of a giant plexiform neurofibroma by double sequential preoperative embolization and surgical resection |
| url | http://dx.doi.org/10.1155/2013/987623 |
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