Diagnosis and Management of Lentigo Maligna: Clinical Presentation and Comprehensive Review
Lentigo maligna (LM), also known as Hutchinson’s melanotic freckle, is a form of in situ melanoma characterized by the proliferation of atypical melanocytes along the basal epidermis in sun-damaged skin. If left untreated, LM will progress to lentigo maligna melanoma (LMM), a form of invasive melano...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Journal of Skin Cancer |
| Online Access: | http://dx.doi.org/10.1155/2021/7178305 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832546042012237824 |
|---|---|
| author | Piyu Parth Naik |
| author_facet | Piyu Parth Naik |
| author_sort | Piyu Parth Naik |
| collection | DOAJ |
| description | Lentigo maligna (LM), also known as Hutchinson’s melanotic freckle, is a form of in situ melanoma characterized by the proliferation of atypical melanocytes along the basal epidermis in sun-damaged skin. If left untreated, LM will progress to lentigo maligna melanoma (LMM), a form of invasive melanoma with the same prognosis as other forms of invasive melanoma. LM is more common in the elderly, with a peak occurrence between the ages of 65 and 80 years. LM, however, is rarely present on the trunk and extremities. The diagnosis of LM, confirmed by histopathological and biopsy examination, is based on clinical and dermoscopic features. It typically begins as a tan-brown macule or patch, but it can progress to a variegated pigmentation with dark black color or even amelanotic characteristics. The risk factors involved in the LM development include a history of sunburns, lighter skin types, advanced age, history of nonmelanoma skin cancers, and tendency to form solar lentigines. This article explains the clinical presentation of LM, also reviews the available information on the diagnosis and management of LM, and discusses the potential of such information in facilitating the future prospective. |
| format | Article |
| id | doaj-art-1a674d694f0e41e2a628a9ce3c9d9298 |
| institution | Kabale University |
| issn | 2090-2905 2090-2913 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Skin Cancer |
| spelling | doaj-art-1a674d694f0e41e2a628a9ce3c9d92982025-02-03T07:24:01ZengWileyJournal of Skin Cancer2090-29052090-29132021-01-01202110.1155/2021/71783057178305Diagnosis and Management of Lentigo Maligna: Clinical Presentation and Comprehensive ReviewPiyu Parth Naik0Department of Dermatology, Saudi German Hospitals and Clinics, Hessa Street 331 West, Al Barsha 3, Exit 36 Sheikh Zayed Road, Opposite of American School, Dubai, UAELentigo maligna (LM), also known as Hutchinson’s melanotic freckle, is a form of in situ melanoma characterized by the proliferation of atypical melanocytes along the basal epidermis in sun-damaged skin. If left untreated, LM will progress to lentigo maligna melanoma (LMM), a form of invasive melanoma with the same prognosis as other forms of invasive melanoma. LM is more common in the elderly, with a peak occurrence between the ages of 65 and 80 years. LM, however, is rarely present on the trunk and extremities. The diagnosis of LM, confirmed by histopathological and biopsy examination, is based on clinical and dermoscopic features. It typically begins as a tan-brown macule or patch, but it can progress to a variegated pigmentation with dark black color or even amelanotic characteristics. The risk factors involved in the LM development include a history of sunburns, lighter skin types, advanced age, history of nonmelanoma skin cancers, and tendency to form solar lentigines. This article explains the clinical presentation of LM, also reviews the available information on the diagnosis and management of LM, and discusses the potential of such information in facilitating the future prospective.http://dx.doi.org/10.1155/2021/7178305 |
| spellingShingle | Piyu Parth Naik Diagnosis and Management of Lentigo Maligna: Clinical Presentation and Comprehensive Review Journal of Skin Cancer |
| title | Diagnosis and Management of Lentigo Maligna: Clinical Presentation and Comprehensive Review |
| title_full | Diagnosis and Management of Lentigo Maligna: Clinical Presentation and Comprehensive Review |
| title_fullStr | Diagnosis and Management of Lentigo Maligna: Clinical Presentation and Comprehensive Review |
| title_full_unstemmed | Diagnosis and Management of Lentigo Maligna: Clinical Presentation and Comprehensive Review |
| title_short | Diagnosis and Management of Lentigo Maligna: Clinical Presentation and Comprehensive Review |
| title_sort | diagnosis and management of lentigo maligna clinical presentation and comprehensive review |
| url | http://dx.doi.org/10.1155/2021/7178305 |
| work_keys_str_mv | AT piyuparthnaik diagnosisandmanagementoflentigomalignaclinicalpresentationandcomprehensivereview |