GOLPH3 promotes calcium oxalate-induced renal injury and fibrosis through Golgi stress-mediated apoptosis and inflammatory responses
Abstract A common urological disorder, calcium oxalate (CaOx) stones are the most common form of kidney stones. Deposition of CaOx crystals leads to tubular damage, interstitial fibrosis, and chronic kidney disease. Understanding the intrinsic mechanisms of kidney stone formation is essential for th...
Saved in:
| Main Authors: | Bao-feng Song, Bo-jun Li, Yushi Sun, Ming Li, Ting Rao, Yuan Ruan, Fan Cheng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-91638-0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Phillyrin prevents calcium oxalate kidney stones through the PPARγ signaling pathway
by: Xiaohan Chu, et al.
Published: (2025-12-01) -
Gut microbiota-regulated unconjugated bilirubin metabolism drives renal calcium oxalate crystal deposition
by: Shujue Li, et al.
Published: (2025-12-01) -
GOLPH3-mTOR Crosstalk and Glycosylation: A Molecular Driver of Cancer Progression
by: Anna Frappaolo, et al.
Published: (2025-03-01) -
Lgals3 Promotes Calcium Oxalate Crystal Formation and Kidney Injury Through Histone Lactylation‐Mediated FGFR4 Activation
by: Zehua Ye, et al.
Published: (2025-03-01) -
GOLPH3 inhibits glioma cell apoptosis through the JNK signaling pathway
by: Shao Xie, et al.
Published: (2025-01-01)