Recurrent Pneumonia due to Fibrosing Mediastinitis in a Teenage Girl: A Case Report with Long-Term Follow-Up
A teenage girl was evaluated for recurrent right pneumonia. The evaluation revealed a calcified mediastinal mass that compressed the right intermediate and middle lobar bronchi, as well as the right pulmonary artery and veins. The clinical picture together with imaging studies and borderline positiv...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2018/3246929 |
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| author | Avigdor Hevroni Chaim Springer Oren Wasser Avraham Avital Benjamin Z. Koplewitz |
| author_facet | Avigdor Hevroni Chaim Springer Oren Wasser Avraham Avital Benjamin Z. Koplewitz |
| author_sort | Avigdor Hevroni |
| collection | DOAJ |
| description | A teenage girl was evaluated for recurrent right pneumonia. The evaluation revealed a calcified mediastinal mass that compressed the right intermediate and middle lobar bronchi, as well as the right pulmonary artery and veins. The clinical picture together with imaging studies and borderline positive serology testing suggested a diagnosis of fibrosing mediastinitis associated with histoplasmosis. This rare condition is characterized by the local proliferation of invasive fibrous tissue within the mediastinum due to a hyperimmune reaction to Histoplasma capsulatum. Antifungal and anti-inflammatory therapies are usually ineffective, and surgical intervention contains a high morbidity risk. Palliative surgery and stenting of the compressed airway have been suggested. In the past, the prognosis was thought to be poor, but recent studies demonstrate a more positive outcome. Our patient had been radiologically and functionally stable under follow-up for over thirteen years and has married and delivered two healthy children, both following an uneventful pregnancy. |
| format | Article |
| id | doaj-art-1a5489248298484793cfab0b735aabb7 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-1a5489248298484793cfab0b735aabb72025-02-03T05:57:54ZengWileyCase Reports in Pediatrics2090-68032090-68112018-01-01201810.1155/2018/32469293246929Recurrent Pneumonia due to Fibrosing Mediastinitis in a Teenage Girl: A Case Report with Long-Term Follow-UpAvigdor Hevroni0Chaim Springer1Oren Wasser2Avraham Avital3Benjamin Z. Koplewitz4Institute of Pulmonology, Hadassah-Hebrew University Medical Center, Jerusalem, IsraelInstitute of Pulmonology, Hadassah-Hebrew University Medical Center, Jerusalem, IsraelInstitute of Pulmonology, Hadassah-Hebrew University Medical Center, Jerusalem, IsraelInstitute of Pulmonology, Hadassah-Hebrew University Medical Center, Jerusalem, IsraelDepartment of Radiology, Hadassah-Hebrew University Medical Center, Jerusalem, IsraelA teenage girl was evaluated for recurrent right pneumonia. The evaluation revealed a calcified mediastinal mass that compressed the right intermediate and middle lobar bronchi, as well as the right pulmonary artery and veins. The clinical picture together with imaging studies and borderline positive serology testing suggested a diagnosis of fibrosing mediastinitis associated with histoplasmosis. This rare condition is characterized by the local proliferation of invasive fibrous tissue within the mediastinum due to a hyperimmune reaction to Histoplasma capsulatum. Antifungal and anti-inflammatory therapies are usually ineffective, and surgical intervention contains a high morbidity risk. Palliative surgery and stenting of the compressed airway have been suggested. In the past, the prognosis was thought to be poor, but recent studies demonstrate a more positive outcome. Our patient had been radiologically and functionally stable under follow-up for over thirteen years and has married and delivered two healthy children, both following an uneventful pregnancy.http://dx.doi.org/10.1155/2018/3246929 |
| spellingShingle | Avigdor Hevroni Chaim Springer Oren Wasser Avraham Avital Benjamin Z. Koplewitz Recurrent Pneumonia due to Fibrosing Mediastinitis in a Teenage Girl: A Case Report with Long-Term Follow-Up Case Reports in Pediatrics |
| title | Recurrent Pneumonia due to Fibrosing Mediastinitis in a Teenage Girl: A Case Report with Long-Term Follow-Up |
| title_full | Recurrent Pneumonia due to Fibrosing Mediastinitis in a Teenage Girl: A Case Report with Long-Term Follow-Up |
| title_fullStr | Recurrent Pneumonia due to Fibrosing Mediastinitis in a Teenage Girl: A Case Report with Long-Term Follow-Up |
| title_full_unstemmed | Recurrent Pneumonia due to Fibrosing Mediastinitis in a Teenage Girl: A Case Report with Long-Term Follow-Up |
| title_short | Recurrent Pneumonia due to Fibrosing Mediastinitis in a Teenage Girl: A Case Report with Long-Term Follow-Up |
| title_sort | recurrent pneumonia due to fibrosing mediastinitis in a teenage girl a case report with long term follow up |
| url | http://dx.doi.org/10.1155/2018/3246929 |
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