Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer Cells
Background: Chemotherapy often leads to encouraging responses in lung cancer. But, in the course of the treatment, resistance to chemotherapy ultimately limits the life expectancy of the patient. We aimed at investigating if treatment with cisplatin alters the intracellular Ca2+-homeostasis of lung...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0472 |
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| _version_ | 1832554482074910720 |
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| author | Kathrin Schrödl Hamza Oelmez Martin Edelmann Rudolf Maria Huber Albrecht Bergner |
| author_facet | Kathrin Schrödl Hamza Oelmez Martin Edelmann Rudolf Maria Huber Albrecht Bergner |
| author_sort | Kathrin Schrödl |
| collection | DOAJ |
| description | Background: Chemotherapy often leads to encouraging responses in lung cancer. But, in the course of the treatment, resistance to chemotherapy ultimately limits the life expectancy of the patient. We aimed at investigating if treatment with cisplatin alters the intracellular Ca2+-homeostasis of lung cancer cells and how this may be related to cisplatin resistance. |
| format | Article |
| id | doaj-art-1a4e7cb95b2d48bb9bba53e0b89cd574 |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-1a4e7cb95b2d48bb9bba53e0b89cd5742025-02-03T05:51:24ZengWileyCellular Oncology1570-58701875-86062009-01-0131430131510.3233/CLO-2009-0472Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer CellsKathrin Schrödl0Hamza Oelmez1Martin Edelmann2Rudolf Maria Huber3Albrecht Bergner4Pneumology, Medizinische Klinik-Innenstadt, Ludwig-Maximilians-University, Munich, GermanyPneumology, Medizinische Klinik-Innenstadt, Ludwig-Maximilians-University, Munich, GermanyPneumology, Medizinische Klinik-Innenstadt, Ludwig-Maximilians-University, Munich, GermanyPneumology, Medizinische Klinik-Innenstadt, Ludwig-Maximilians-University, Munich, GermanyPneumology, Medizinische Klinik-Innenstadt, Ludwig-Maximilians-University, Munich, GermanyBackground: Chemotherapy often leads to encouraging responses in lung cancer. But, in the course of the treatment, resistance to chemotherapy ultimately limits the life expectancy of the patient. We aimed at investigating if treatment with cisplatin alters the intracellular Ca2+-homeostasis of lung cancer cells and how this may be related to cisplatin resistance.http://dx.doi.org/10.3233/CLO-2009-0472 |
| spellingShingle | Kathrin Schrödl Hamza Oelmez Martin Edelmann Rudolf Maria Huber Albrecht Bergner Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer Cells Cellular Oncology |
| title | Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer Cells |
| title_full | Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer Cells |
| title_fullStr | Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer Cells |
| title_full_unstemmed | Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer Cells |
| title_short | Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer Cells |
| title_sort | altered ca2 homeostasis of cisplatin treated and low level resistant non small cell and small cell lung cancer cells |
| url | http://dx.doi.org/10.3233/CLO-2009-0472 |
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