Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 Cases
An association exists between colon carcinoma and Clostridium septicum infection, especially bacteremia. We reviewed retrospectively all positive blood cultures for this organism at a 300-bed general hospital over 4 years. Four of 15 cases were associated with concurrent colon carcinoma. C. septicum...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/248453 |
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| author | Eric Mao Aine Clements Edward Feller |
| author_facet | Eric Mao Aine Clements Edward Feller |
| author_sort | Eric Mao |
| collection | DOAJ |
| description | An association exists between colon carcinoma and Clostridium septicum infection, especially bacteremia. We reviewed retrospectively all positive blood cultures for this organism at a 300-bed general hospital over 4 years. Four of 15 cases were associated with concurrent colon carcinoma. C. septicum infection was the presenting feature of previously undiagnosed large bowel malignancy in three patients. We report this small case series to alert clinicians to the diverse spectrum and diagnostic difficulties of this rare, potentially catastrophic association. Although commonly associated with necrotizing skin or soft tissue infections, this bacterium can present with nonspecific or atypical symptoms. All patients with positive blood cultures for C. septicum, even without clinical suspicion of large bowel malignancy, should undergo colonoscopy to evaluate for colon carcinoma. |
| format | Article |
| id | doaj-art-1a4c25fe316649138dfad69a2e459cdc |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-1a4c25fe316649138dfad69a2e459cdc2025-02-03T05:44:57ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/248453248453Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 CasesEric Mao0Aine Clements1Edward Feller2The Warren Alpert Medical School of Brown University, Providence, RI 02912, USADivision of Gynecologic Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USAThe Warren Alpert Medical School of Brown University, Providence, RI 02912, USAAn association exists between colon carcinoma and Clostridium septicum infection, especially bacteremia. We reviewed retrospectively all positive blood cultures for this organism at a 300-bed general hospital over 4 years. Four of 15 cases were associated with concurrent colon carcinoma. C. septicum infection was the presenting feature of previously undiagnosed large bowel malignancy in three patients. We report this small case series to alert clinicians to the diverse spectrum and diagnostic difficulties of this rare, potentially catastrophic association. Although commonly associated with necrotizing skin or soft tissue infections, this bacterium can present with nonspecific or atypical symptoms. All patients with positive blood cultures for C. septicum, even without clinical suspicion of large bowel malignancy, should undergo colonoscopy to evaluate for colon carcinoma.http://dx.doi.org/10.1155/2011/248453 |
| spellingShingle | Eric Mao Aine Clements Edward Feller Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 Cases Case Reports in Medicine |
| title | Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 Cases |
| title_full | Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 Cases |
| title_fullStr | Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 Cases |
| title_full_unstemmed | Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 Cases |
| title_short | Clostridium septicum Sepsis and Colon Carcinoma: Report of 4 Cases |
| title_sort | clostridium septicum sepsis and colon carcinoma report of 4 cases |
| url | http://dx.doi.org/10.1155/2011/248453 |
| work_keys_str_mv | AT ericmao clostridiumsepticumsepsisandcoloncarcinomareportof4cases AT aineclements clostridiumsepticumsepsisandcoloncarcinomareportof4cases AT edwardfeller clostridiumsepticumsepsisandcoloncarcinomareportof4cases |