Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles
Objective. To compare the cytology quality of ultrasound-guided fine-needle biopsy in thyroid nodules with 22-, 23-, and 25-gauge (G) needles prospectively. Methods. A total of 240 consecutive nodules underwent ultrasound-guided fine-needle aspiration (USG-FNA) and 240 nodules underwent ultrasound-g...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.1155/2021/5544921 |
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| author | YiJie Dong LiLi Gao Yang Sui MinJing Mao WeiWei Zhan JianQiao Zhou |
| author_facet | YiJie Dong LiLi Gao Yang Sui MinJing Mao WeiWei Zhan JianQiao Zhou |
| author_sort | YiJie Dong |
| collection | DOAJ |
| description | Objective. To compare the cytology quality of ultrasound-guided fine-needle biopsy in thyroid nodules with 22-, 23-, and 25-gauge (G) needles prospectively. Methods. A total of 240 consecutive nodules underwent ultrasound-guided fine-needle aspiration (USG-FNA) and 240 nodules underwent ultrasound-guided fine-needle capillary (USG-FNC) were included in this prospective study from October 2014 to February 2016. Each nodule was sampled using 22 G, 23 G, and 25 G needle according to designed orders, and 1240 smears were finally obtained. Cytology quality was scored by a cytologist blinded to needle selection. Results. In USG-FNA, the average scores and standard deviations were 5.50±2.87 for 25 G needles, 4.82±2.95 for 23 G needles, and 5.19±2.81 for 22 G needles. In USG-FNC, the average scores and standard deviations of each group were 5.12±2.69 for 25 G, 4.60±2.90 for 23 G, and 4.90±2.90 for 22 G needles. The specimen quality scores of 25 G group were significantly higher than that of 23 G group (P<0.017) in both USG-FNA and USG-FNC. However, the differences were not statistically significant in nondiagnostic rate using different gauge of needles (P>0.017 for all). Conclusions. 25 G needles obtained the highest scores of sample quality in thyroid FNA and FNC comparing with 22 G and 23 G needles. 25 G needle should be first choice of thyroid FNA and FNC in routine work. |
| format | Article |
| id | doaj-art-1a203b9914a3467a803015c7c0aa2831 |
| institution | Kabale University |
| issn | 2210-7177 2210-7185 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-1a203b9914a3467a803015c7c0aa28312025-02-03T01:05:12ZengWileyAnalytical Cellular Pathology2210-71772210-71852021-01-01202110.1155/2021/55449215544921Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge NeedlesYiJie Dong0LiLi Gao1Yang Sui2MinJing Mao3WeiWei Zhan4JianQiao Zhou5Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University Medical School, Shanghai 200025, ChinaDepartment of Pathology, Ruijin Hospital, Shanghai Jiaotong University Medical School, Shanghai 200025, ChinaDepartment of Ultrasound, First Affiliated Hospital of Bengbu Medical College, Bengbu 233000, ChinaDepartment of Laboratory, Ruijin Hospital, Shanghai Jiaotong University Medical School, Shanghai 200025, ChinaDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University Medical School, Shanghai 200025, ChinaDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University Medical School, Shanghai 200025, ChinaObjective. To compare the cytology quality of ultrasound-guided fine-needle biopsy in thyroid nodules with 22-, 23-, and 25-gauge (G) needles prospectively. Methods. A total of 240 consecutive nodules underwent ultrasound-guided fine-needle aspiration (USG-FNA) and 240 nodules underwent ultrasound-guided fine-needle capillary (USG-FNC) were included in this prospective study from October 2014 to February 2016. Each nodule was sampled using 22 G, 23 G, and 25 G needle according to designed orders, and 1240 smears were finally obtained. Cytology quality was scored by a cytologist blinded to needle selection. Results. In USG-FNA, the average scores and standard deviations were 5.50±2.87 for 25 G needles, 4.82±2.95 for 23 G needles, and 5.19±2.81 for 22 G needles. In USG-FNC, the average scores and standard deviations of each group were 5.12±2.69 for 25 G, 4.60±2.90 for 23 G, and 4.90±2.90 for 22 G needles. The specimen quality scores of 25 G group were significantly higher than that of 23 G group (P<0.017) in both USG-FNA and USG-FNC. However, the differences were not statistically significant in nondiagnostic rate using different gauge of needles (P>0.017 for all). Conclusions. 25 G needles obtained the highest scores of sample quality in thyroid FNA and FNC comparing with 22 G and 23 G needles. 25 G needle should be first choice of thyroid FNA and FNC in routine work.http://dx.doi.org/10.1155/2021/5544921 |
| spellingShingle | YiJie Dong LiLi Gao Yang Sui MinJing Mao WeiWei Zhan JianQiao Zhou Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles Analytical Cellular Pathology |
| title | Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles |
| title_full | Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles |
| title_fullStr | Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles |
| title_full_unstemmed | Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles |
| title_short | Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles |
| title_sort | comparison of ultrasound guided fine needle cytology quality in thyroid nodules with 22 23 and 25 gauge needles |
| url | http://dx.doi.org/10.1155/2021/5544921 |
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