Sod1 deficiency reduces incubation time in mouse models of prion disease.

Sod1 deficiency reduces incubation time in mouse models of prion disease.

Prion infections, causing neurodegenerative conditions such as Creutzfeldt-Jakob disease and kuru in humans, scrapie in sheep and BSE in cattle are characterised by prolonged and variable incubation periods that are faithfully reproduced in mouse models. Incubation time is partly determined by genet...

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Bibliographic Details
Main Authors: Shaheen Akhtar, Julia Grizenkova, Adam Wenborn, Holger Hummerich, Mar Fernandez de Marco, Sebastian Brandner, John Collinge, Sarah E Lloyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0054454&type=printable
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