Intestinal Tuberculosis Masquerading as Crohn’s Disease? A Case of Disseminated Tuberculosis after Anti-TNF Therapy for Suspected Crohn’s Disease

Intestinal tuberculosis (ITB) and Crohn’s disease (CD) very closely resemble each other in symptomatology, imaging, appearance, and pathology. While ITB is rare in the United States, its prevalence is significantly higher in endemic areas, thus presenting a diagnostic dilemma in immigrant population...

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Main Authors: Alexander P. Abadir, James Y. Han, Fady A. Youssef
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2019/6053503
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author Alexander P. Abadir
James Y. Han
Fady A. Youssef
author_facet Alexander P. Abadir
James Y. Han
Fady A. Youssef
author_sort Alexander P. Abadir
collection DOAJ
description Intestinal tuberculosis (ITB) and Crohn’s disease (CD) very closely resemble each other in symptomatology, imaging, appearance, and pathology. While ITB is rare in the United States, its prevalence is significantly higher in endemic areas, thus presenting a diagnostic dilemma in immigrant populations from high-risk countries. This patient was diagnosed with CD and treated with anti-TNF agents after indeterminate screening for latent tuberculosis. He was then admitted with septic shock and intestinal perforation due to disseminated tuberculosis. This case demonstrates the importance the consideration of ITB when a patient with risk factors for TB fails to respond to treatment for CD.
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institution Kabale University
issn 2090-6528
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publishDate 2019-01-01
publisher Wiley
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-1a0d8a0ddbd74bf09b39c47b2092b9d72025-02-03T00:59:03ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362019-01-01201910.1155/2019/60535036053503Intestinal Tuberculosis Masquerading as Crohn’s Disease? A Case of Disseminated Tuberculosis after Anti-TNF Therapy for Suspected Crohn’s DiseaseAlexander P. Abadir0James Y. Han1Fady A. Youssef2University of California Irvine Medical Center, Orange, USAUniversity of California Irvine Medical Center, Orange, USAUniversity of California Irvine Medical Center, Orange, USAIntestinal tuberculosis (ITB) and Crohn’s disease (CD) very closely resemble each other in symptomatology, imaging, appearance, and pathology. While ITB is rare in the United States, its prevalence is significantly higher in endemic areas, thus presenting a diagnostic dilemma in immigrant populations from high-risk countries. This patient was diagnosed with CD and treated with anti-TNF agents after indeterminate screening for latent tuberculosis. He was then admitted with septic shock and intestinal perforation due to disseminated tuberculosis. This case demonstrates the importance the consideration of ITB when a patient with risk factors for TB fails to respond to treatment for CD.http://dx.doi.org/10.1155/2019/6053503
spellingShingle Alexander P. Abadir
James Y. Han
Fady A. Youssef
Intestinal Tuberculosis Masquerading as Crohn’s Disease? A Case of Disseminated Tuberculosis after Anti-TNF Therapy for Suspected Crohn’s Disease
Case Reports in Gastrointestinal Medicine
title Intestinal Tuberculosis Masquerading as Crohn’s Disease? A Case of Disseminated Tuberculosis after Anti-TNF Therapy for Suspected Crohn’s Disease
title_full Intestinal Tuberculosis Masquerading as Crohn’s Disease? A Case of Disseminated Tuberculosis after Anti-TNF Therapy for Suspected Crohn’s Disease
title_fullStr Intestinal Tuberculosis Masquerading as Crohn’s Disease? A Case of Disseminated Tuberculosis after Anti-TNF Therapy for Suspected Crohn’s Disease
title_full_unstemmed Intestinal Tuberculosis Masquerading as Crohn’s Disease? A Case of Disseminated Tuberculosis after Anti-TNF Therapy for Suspected Crohn’s Disease
title_short Intestinal Tuberculosis Masquerading as Crohn’s Disease? A Case of Disseminated Tuberculosis after Anti-TNF Therapy for Suspected Crohn’s Disease
title_sort intestinal tuberculosis masquerading as crohn s disease a case of disseminated tuberculosis after anti tnf therapy for suspected crohn s disease
url http://dx.doi.org/10.1155/2019/6053503
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