Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy
Purpose. To describe frequency, clinical characteristics, and visual prognosis of tubercular uveitis (TBU) in a nonendemic country. Methods. We retrospectively reviewed 3743 charts of patients with endogenous uveitis visited from 2008 to 2018 at a tertiary referral centre in Rome, Italy. We included...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2020/4701820 |
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| author | M. La Cava A. Bruscolini M. Sacchetti M. P. Pirraglia A. Moramarco M. Marenco G. Iaiani G. Covelli T. Rizzo I. Abicca A. Lambiase |
| author_facet | M. La Cava A. Bruscolini M. Sacchetti M. P. Pirraglia A. Moramarco M. Marenco G. Iaiani G. Covelli T. Rizzo I. Abicca A. Lambiase |
| author_sort | M. La Cava |
| collection | DOAJ |
| description | Purpose. To describe frequency, clinical characteristics, and visual prognosis of tubercular uveitis (TBU) in a nonendemic country. Methods. We retrospectively reviewed 3743 charts of patients with endogenous uveitis visited from 2008 to 2018 at a tertiary referral centre in Rome, Italy. We included immunocompetent patients with diagnosis of TBU. Patients were divided in two groups: patients with history of uveitis without a previous diagnosis of TBU (group A) and patients at their first episode of TB uveitis (group B). Results. TBU was diagnosed in 28 (0.75%) out of 3743 patients. Twelve (42.9%) patients came from tuberculosis endemic areas. All patients received specific antitubercular treatment (ATT) and were evaluated for a mean follow-up of 3.2 ± 2.9 years. Group A showed a greater number of ocular complications when compared with group B. ATT was effective in reducing the frequency of recurrences of uveitis in patients of group B. Conclusion. Intraocular inflammation can be the first manifestation of tuberculosis. Our data highlight that early diagnosis and specific treatment of TBU may allow to decrease recurrences and to improve visual outcomes. |
| format | Article |
| id | doaj-art-19e667e0a29c4111afea0e97bdd0b591 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-19e667e0a29c4111afea0e97bdd0b5912025-02-03T06:45:46ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/47018204701820Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in ItalyM. La Cava0A. Bruscolini1M. Sacchetti2M. P. Pirraglia3A. Moramarco4M. Marenco5G. Iaiani6G. Covelli7T. Rizzo8I. Abicca9A. Lambiase10Department of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyDepartment of Sense Organs, Sapienza University of Rome, Rome, ItalyPurpose. To describe frequency, clinical characteristics, and visual prognosis of tubercular uveitis (TBU) in a nonendemic country. Methods. We retrospectively reviewed 3743 charts of patients with endogenous uveitis visited from 2008 to 2018 at a tertiary referral centre in Rome, Italy. We included immunocompetent patients with diagnosis of TBU. Patients were divided in two groups: patients with history of uveitis without a previous diagnosis of TBU (group A) and patients at their first episode of TB uveitis (group B). Results. TBU was diagnosed in 28 (0.75%) out of 3743 patients. Twelve (42.9%) patients came from tuberculosis endemic areas. All patients received specific antitubercular treatment (ATT) and were evaluated for a mean follow-up of 3.2 ± 2.9 years. Group A showed a greater number of ocular complications when compared with group B. ATT was effective in reducing the frequency of recurrences of uveitis in patients of group B. Conclusion. Intraocular inflammation can be the first manifestation of tuberculosis. Our data highlight that early diagnosis and specific treatment of TBU may allow to decrease recurrences and to improve visual outcomes.http://dx.doi.org/10.1155/2020/4701820 |
| spellingShingle | M. La Cava A. Bruscolini M. Sacchetti M. P. Pirraglia A. Moramarco M. Marenco G. Iaiani G. Covelli T. Rizzo I. Abicca A. Lambiase Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy Journal of Ophthalmology |
| title | Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy |
| title_full | Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy |
| title_fullStr | Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy |
| title_full_unstemmed | Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy |
| title_short | Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy |
| title_sort | clinical and epidemiological study on tubercular uveitis in a tertiary eye care centre in italy |
| url | http://dx.doi.org/10.1155/2020/4701820 |
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