Postmenopausal Hyperandrogenism due to Ovarian Hyperthecosis

Ovarian hyperthecosis or ovarian stromal hyperplasia is a non-neoplastic functional disorder resulting from the presence of luteinized thecal cells within a hyperplastic ovarian stroma. The condition is more common in postmenopausal women than in those of reproductive age and leads to substantial cl...

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Main Authors: Laryssa Santos Metzker, Luyanne Azevedo Cabral Ferreira, Julia Caroliny Nogueira Borges, Mariana Furieri Guzzo, Rodrigo Neves Ferreira, Lucas Luciano Rocha Silva, Rodrigo Monico Cavedo, Antonio Chambô Filho
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2023/2783464
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author Laryssa Santos Metzker
Luyanne Azevedo Cabral Ferreira
Julia Caroliny Nogueira Borges
Mariana Furieri Guzzo
Rodrigo Neves Ferreira
Lucas Luciano Rocha Silva
Rodrigo Monico Cavedo
Antonio Chambô Filho
author_facet Laryssa Santos Metzker
Luyanne Azevedo Cabral Ferreira
Julia Caroliny Nogueira Borges
Mariana Furieri Guzzo
Rodrigo Neves Ferreira
Lucas Luciano Rocha Silva
Rodrigo Monico Cavedo
Antonio Chambô Filho
author_sort Laryssa Santos Metzker
collection DOAJ
description Ovarian hyperthecosis or ovarian stromal hyperplasia is a non-neoplastic functional disorder resulting from the presence of luteinized thecal cells within a hyperplastic ovarian stroma. The condition is more common in postmenopausal women than in those of reproductive age and leads to substantial clinical and laboratory alterations, principally androgenetic alopecia, progressive hirsutism, and elevated testosterone levels. Investigation should include clinical evaluation, laboratory tests, and imaging tests to differentiate between the principal diagnostic hypotheses. The gold standard for diagnosis is histopathology of the ovarian tissue. The present case report describes a woman being followed up as an outpatient at the Santa Casa de Misericórdia Hospital in Vitória, Brazil. The objective in publishing this case report is to add to available data on ovarian hyperthecosis, thus contributing towards improving timely diagnosis and treatment. Early diagnosis and treatment would ensure better quality of life for patients with this condition and better physical and mental health. Moreover, these data should be useful both for the medical community and for future research into this disease.
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institution Kabale University
issn 2090-6692
language English
publishDate 2023-01-01
publisher Wiley
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-19e2b149f96b4b2c8169ad2a3fdd71d22025-08-20T03:54:21ZengWileyCase Reports in Obstetrics and Gynecology2090-66922023-01-01202310.1155/2023/2783464Postmenopausal Hyperandrogenism due to Ovarian HyperthecosisLaryssa Santos Metzker0Luyanne Azevedo Cabral Ferreira1Julia Caroliny Nogueira Borges2Mariana Furieri Guzzo3Rodrigo Neves Ferreira4Lucas Luciano Rocha Silva5Rodrigo Monico Cavedo6Antonio Chambô Filho7Santa Casa de Misericórdia de Vitória HospitalSanta Casa de Misericórdia de Vitória HospitalSanta Casa de Misericórdia de Vitória HospitalSanta Casa de Misericórdia de Vitória HospitalSanta Casa de Misericórdia de Vitória HospitalSanta Casa de Misericórdia de Vitória HospitalSanta Casa de Misericórdia de Vitória HospitalSanta Casa de Misericórdia de Vitória HospitalOvarian hyperthecosis or ovarian stromal hyperplasia is a non-neoplastic functional disorder resulting from the presence of luteinized thecal cells within a hyperplastic ovarian stroma. The condition is more common in postmenopausal women than in those of reproductive age and leads to substantial clinical and laboratory alterations, principally androgenetic alopecia, progressive hirsutism, and elevated testosterone levels. Investigation should include clinical evaluation, laboratory tests, and imaging tests to differentiate between the principal diagnostic hypotheses. The gold standard for diagnosis is histopathology of the ovarian tissue. The present case report describes a woman being followed up as an outpatient at the Santa Casa de Misericórdia Hospital in Vitória, Brazil. The objective in publishing this case report is to add to available data on ovarian hyperthecosis, thus contributing towards improving timely diagnosis and treatment. Early diagnosis and treatment would ensure better quality of life for patients with this condition and better physical and mental health. Moreover, these data should be useful both for the medical community and for future research into this disease.http://dx.doi.org/10.1155/2023/2783464
spellingShingle Laryssa Santos Metzker
Luyanne Azevedo Cabral Ferreira
Julia Caroliny Nogueira Borges
Mariana Furieri Guzzo
Rodrigo Neves Ferreira
Lucas Luciano Rocha Silva
Rodrigo Monico Cavedo
Antonio Chambô Filho
Postmenopausal Hyperandrogenism due to Ovarian Hyperthecosis
Case Reports in Obstetrics and Gynecology
title Postmenopausal Hyperandrogenism due to Ovarian Hyperthecosis
title_full Postmenopausal Hyperandrogenism due to Ovarian Hyperthecosis
title_fullStr Postmenopausal Hyperandrogenism due to Ovarian Hyperthecosis
title_full_unstemmed Postmenopausal Hyperandrogenism due to Ovarian Hyperthecosis
title_short Postmenopausal Hyperandrogenism due to Ovarian Hyperthecosis
title_sort postmenopausal hyperandrogenism due to ovarian hyperthecosis
url http://dx.doi.org/10.1155/2023/2783464
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