Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly
Abstract Particle manipulation plays a pivotal role in scientific and technological domains such as materials science, physics, and the life sciences. Here, we present a dynamically reconfigurable acoustofluidic metasurface that enables precise trapping and positioning of microscale particles in flu...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-55337-0 |
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| author | Sushruta Surappa Suraj Pavagada Fernando Soto Demir Akin Charles Wei F. Levent Degertekin Utkan Demirci |
| author_facet | Sushruta Surappa Suraj Pavagada Fernando Soto Demir Akin Charles Wei F. Levent Degertekin Utkan Demirci |
| author_sort | Sushruta Surappa |
| collection | DOAJ |
| description | Abstract Particle manipulation plays a pivotal role in scientific and technological domains such as materials science, physics, and the life sciences. Here, we present a dynamically reconfigurable acoustofluidic metasurface that enables precise trapping and positioning of microscale particles in fluidic environments. By harnessing acoustic-structure interaction in a passive membrane resonator array, we generate localized standing acoustic waves that can be reconfigured in real-time. The resulting radiation force allows for subwavelength manipulation and patterning of particles on the metasurface at individual and collective scales, with actuation frequencies below 2 MHz. We further demonstrate the capabilities of the reconfigurable metasurface in trapping and enriching beads and biological cells flowing in microfluidic channels, showcasing its potential in high-throughput bioanalytical applications. Our versatile and biocompatible particle manipulation platform is suitable for applications ranging from the assembly of colloidal particles to enrichment of rare cells. |
| format | Article |
| id | doaj-art-19dccd0a664c4a54b211c0d05d7d0ca0 |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-19dccd0a664c4a54b211c0d05d7d0ca02025-01-19T12:30:56ZengNature PortfolioNature Communications2041-17232025-01-0116111010.1038/s41467-024-55337-0Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assemblySushruta Surappa0Suraj Pavagada1Fernando Soto2Demir Akin3Charles Wei4F. Levent Degertekin5Utkan Demirci6Bio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford, Department of Radiology, School of Medicine, Stanford UniversityBio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford, Department of Radiology, School of Medicine, Stanford UniversityBio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford, Department of Radiology, School of Medicine, Stanford UniversityBio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford, Department of Radiology, School of Medicine, Stanford UniversityGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of TechnologyGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of TechnologyBio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford, Department of Radiology, School of Medicine, Stanford UniversityAbstract Particle manipulation plays a pivotal role in scientific and technological domains such as materials science, physics, and the life sciences. Here, we present a dynamically reconfigurable acoustofluidic metasurface that enables precise trapping and positioning of microscale particles in fluidic environments. By harnessing acoustic-structure interaction in a passive membrane resonator array, we generate localized standing acoustic waves that can be reconfigured in real-time. The resulting radiation force allows for subwavelength manipulation and patterning of particles on the metasurface at individual and collective scales, with actuation frequencies below 2 MHz. We further demonstrate the capabilities of the reconfigurable metasurface in trapping and enriching beads and biological cells flowing in microfluidic channels, showcasing its potential in high-throughput bioanalytical applications. Our versatile and biocompatible particle manipulation platform is suitable for applications ranging from the assembly of colloidal particles to enrichment of rare cells.https://doi.org/10.1038/s41467-024-55337-0 |
| spellingShingle | Sushruta Surappa Suraj Pavagada Fernando Soto Demir Akin Charles Wei F. Levent Degertekin Utkan Demirci Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly Nature Communications |
| title | Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly |
| title_full | Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly |
| title_fullStr | Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly |
| title_full_unstemmed | Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly |
| title_short | Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly |
| title_sort | dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly |
| url | https://doi.org/10.1038/s41467-024-55337-0 |
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