Synthesis, Antibacterial and Antifungal Activities of s Derivatives

Several Nʹ-{4-[(3-chloro-4-fluorophenyl) amino]-6-[(-aryl) amino] -1, 3, 5-triazin-2-yl} isonicotinohydrazides (6a-r) and N2-(Aryl)-N4, N6-dipyrimidin-2-yl-1,3,5-triazine-2,4,6-triamines (4a-o) were prepared. All newly synthesized compounds have been tested for their antibacterial activity against g...

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Main Authors: B. B. Baldaniya, P. K. Patel
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2009/196309
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author B. B. Baldaniya
P. K. Patel
author_facet B. B. Baldaniya
P. K. Patel
author_sort B. B. Baldaniya
collection DOAJ
description Several Nʹ-{4-[(3-chloro-4-fluorophenyl) amino]-6-[(-aryl) amino] -1, 3, 5-triazin-2-yl} isonicotinohydrazides (6a-r) and N2-(Aryl)-N4, N6-dipyrimidin-2-yl-1,3,5-triazine-2,4,6-triamines (4a-o) were prepared. All newly synthesized compounds have been tested for their antibacterial activity against gram (+)ve and gram (-)ve bacteria and also on different strains of fungi. Introduction of -OH, -OCH3, -NO2, -Cl and -Br groups to the heterocyclic frame work enhanced antibacterial and antifungal activities.
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issn 0973-4945
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publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-19d4afb70c3f4bd78b9a197d52100aef2025-02-03T05:52:16ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-016367368010.1155/2009/196309Synthesis, Antibacterial and Antifungal Activities of s DerivativesB. B. Baldaniya0P. K. Patel1Department of Chemistry, M. G. Science Institute, Navarangpura, Ahmedabad-380 009, Gujarat, IndiaDepartment of Chemistry, M. G. Science Institute, Navarangpura, Ahmedabad-380 009, Gujarat, IndiaSeveral Nʹ-{4-[(3-chloro-4-fluorophenyl) amino]-6-[(-aryl) amino] -1, 3, 5-triazin-2-yl} isonicotinohydrazides (6a-r) and N2-(Aryl)-N4, N6-dipyrimidin-2-yl-1,3,5-triazine-2,4,6-triamines (4a-o) were prepared. All newly synthesized compounds have been tested for their antibacterial activity against gram (+)ve and gram (-)ve bacteria and also on different strains of fungi. Introduction of -OH, -OCH3, -NO2, -Cl and -Br groups to the heterocyclic frame work enhanced antibacterial and antifungal activities.http://dx.doi.org/10.1155/2009/196309
spellingShingle B. B. Baldaniya
P. K. Patel
Synthesis, Antibacterial and Antifungal Activities of s Derivatives
E-Journal of Chemistry
title Synthesis, Antibacterial and Antifungal Activities of s Derivatives
title_full Synthesis, Antibacterial and Antifungal Activities of s Derivatives
title_fullStr Synthesis, Antibacterial and Antifungal Activities of s Derivatives
title_full_unstemmed Synthesis, Antibacterial and Antifungal Activities of s Derivatives
title_short Synthesis, Antibacterial and Antifungal Activities of s Derivatives
title_sort synthesis antibacterial and antifungal activities of s derivatives
url http://dx.doi.org/10.1155/2009/196309
work_keys_str_mv AT bbbaldaniya synthesisantibacterialandantifungalactivitiesofsderivatives
AT pkpatel synthesisantibacterialandantifungalactivitiesofsderivatives