BrnQ Branched-Chain Amino Acid Transporters Influence Toxin Production by, but Not Growth of, <i>Clostridium perfringens</i> Type A Strain ATCC3624

BrnQ Branched-Chain Amino Acid Transporters Influence Toxin Production by, but Not Growth of, <i>Clostridium perfringens</i> Type A Strain ATCC3624

By producing alpha toxin (PLC) and perfringolysin O (PFO), <i>Clostridium perfringens</i> type A strains are the most common cause of traumatic gas gangrene. <i>C. perfringens</i> cannot synthesize branched-chain amino acids (BCAAs), so BCAA transporters are essential for <...

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Bibliographic Details
Main Authors: Jihong Li, Iman Mehdizadeh Gohari, Isabella Zhang, Bruce A. McClane
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Toxins
Subjects:
<i>Clostridium perfringens</i>
BrnQ transporters
alpha toxin
perfringolysin O
regulation
Online Access:https://www.mdpi.com/2072-6651/17/4/187
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