ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser

The software package GeneExpressionAnalyser for analysis of the DNA microarray experi-mental data has been developed. The algorithms of data analysis, differentially expressed genes and biological functions of the cell are described. The efficiency of the developed package is tested on the published...

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Main Authors: A. V. Saetchnikov, M. M. Yatskou, P. V. Nazarov, L. Vallar, V. V. Apanasovich
Format: Article
Language:Russian
Published: National Academy of Sciences of Belarus, the United Institute of Informatics Problems 2016-10-01
Series:Informatika
Online Access:https://inf.grid.by/jour/article/view/142
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author A. V. Saetchnikov
M. M. Yatskou
P. V. Nazarov
L. Vallar
V. V. Apanasovich
author_facet A. V. Saetchnikov
M. M. Yatskou
P. V. Nazarov
L. Vallar
V. V. Apanasovich
author_sort A. V. Saetchnikov
collection DOAJ
description The software package GeneExpressionAnalyser for analysis of the DNA microarray experi-mental data has been developed. The algorithms of data analysis, differentially expressed genes and biological functions of the cell are described. The efficiency of the developed package is tested on the published experimental data devoted to the time-course research of the changes in the human cell un-der the influence of IFN-γ on melanoma. The developed software has a number of advantages over the existing software: it is free, has a simple and intuitive graphical interface, allows to analyze different types of DNA microarrays, contains a set of methods for complete data analysis and performs effec-tive gene annotation for a selected list of genes.
format Article
id doaj-art-19b3e1d640eb423fa49ac338f0f2d942
institution Kabale University
issn 1816-0301
language Russian
publishDate 2016-10-01
publisher National Academy of Sciences of Belarus, the United Institute of Informatics Problems
record_format Article
series Informatika
spelling doaj-art-19b3e1d640eb423fa49ac338f0f2d9422025-02-03T11:51:49ZrusNational Academy of Sciences of Belarus, the United Institute of Informatics ProblemsInformatika1816-03012016-10-01028497141ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyserA. V. Saetchnikov0M. M. Yatskou1P. V. Nazarov2L. Vallar3V. V. Apanasovich4Белорусский государственный университетБелорусский государственный университетЦентр геномных исследованийЦентр геномных исследованийБелорусский государственный университетThe software package GeneExpressionAnalyser for analysis of the DNA microarray experi-mental data has been developed. The algorithms of data analysis, differentially expressed genes and biological functions of the cell are described. The efficiency of the developed package is tested on the published experimental data devoted to the time-course research of the changes in the human cell un-der the influence of IFN-γ on melanoma. The developed software has a number of advantages over the existing software: it is free, has a simple and intuitive graphical interface, allows to analyze different types of DNA microarrays, contains a set of methods for complete data analysis and performs effec-tive gene annotation for a selected list of genes.https://inf.grid.by/jour/article/view/142
spellingShingle A. V. Saetchnikov
M. M. Yatskou
P. V. Nazarov
L. Vallar
V. V. Apanasovich
ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser
Informatika
title ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser
title_full ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser
title_fullStr ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser
title_full_unstemmed ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser
title_short ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser
title_sort analysis of cellular reaction to ifn γ stimulation by a software package geneexpressionanalyser
url https://inf.grid.by/jour/article/view/142
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