A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies
The vascularity of placental tissue is dependent on various factors of which fetomaternal hypoxia plays a major role. Hypoxia can be of different types and each type influences the vascularity of the villi, especially terminal villi, in its own way. In this study, we attempted to identify villous va...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2014/193925 |
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| author | Anu Priyadharshini Srinivasan B. O. Parijatham Omprakash Kandhimalla Lavanya Priyadharshini Subbulakshmi Murugesan Saraswathi Kandaswamy |
| author_facet | Anu Priyadharshini Srinivasan B. O. Parijatham Omprakash Kandhimalla Lavanya Priyadharshini Subbulakshmi Murugesan Saraswathi Kandaswamy |
| author_sort | Anu Priyadharshini Srinivasan |
| collection | DOAJ |
| description | The vascularity of placental tissue is dependent on various factors of which fetomaternal hypoxia plays a major role. Hypoxia can be of different types and each type influences the vascularity of the villi, especially terminal villi, in its own way. In this study, we attempted to identify villous vascular changes in a group of term placentae from mothers with diseases complicating pregnancy. Chorangiosis was the most frequently identified lesion while chorangioma was found in only 2 cases. There were no cases of chorangiomatosis. A few cases had normal villous vasculature. Maternal diseases have a major role in disrupting the placental vasculogenesis and angiogenesis by creating a hypoxic environment that may affect the fetus adversely. Hence, such conditions need to be identified early in pregnancy and managed appropriately as it is possible to maintain a normal vasculature and prevent neonatal mortality and morbidity if prompt intervention is done. |
| format | Article |
| id | doaj-art-19b275bea17d4b428297c879f3e076fc |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-19b275bea17d4b428297c879f3e076fc2025-02-03T01:22:50ZengWileyJournal of Pregnancy2090-27272090-27352014-01-01201410.1155/2014/193925193925A Prospective Study of Villous Capillary Lesions in Complicated PregnanciesAnu Priyadharshini Srinivasan0B. O. Parijatham Omprakash1Kandhimalla Lavanya2Priyadharshini Subbulakshmi Murugesan3Saraswathi Kandaswamy4Department of Pathology, Sree Balaji Medical College and Hospital, Bharath University, Chennai, Tamil Nadu 600 044, IndiaDepartment of Pathology, Sree Balaji Medical College and Hospital, Bharath University, Chennai, Tamil Nadu 600 044, IndiaDepartment of Obstetrics and Gynaecology, Sree Balaji Medical College and Hospital, Bharath University, Chennai, Tamil Nadu 600 044, IndiaDepartment of Obstetrics and Gynaecology, Sree Balaji Medical College and Hospital, Bharath University, Chennai, Tamil Nadu 600 044, IndiaDepartment of Obstetrics and Gynaecology, Sree Balaji Medical College and Hospital, Bharath University, Chennai, Tamil Nadu 600 044, IndiaThe vascularity of placental tissue is dependent on various factors of which fetomaternal hypoxia plays a major role. Hypoxia can be of different types and each type influences the vascularity of the villi, especially terminal villi, in its own way. In this study, we attempted to identify villous vascular changes in a group of term placentae from mothers with diseases complicating pregnancy. Chorangiosis was the most frequently identified lesion while chorangioma was found in only 2 cases. There were no cases of chorangiomatosis. A few cases had normal villous vasculature. Maternal diseases have a major role in disrupting the placental vasculogenesis and angiogenesis by creating a hypoxic environment that may affect the fetus adversely. Hence, such conditions need to be identified early in pregnancy and managed appropriately as it is possible to maintain a normal vasculature and prevent neonatal mortality and morbidity if prompt intervention is done.http://dx.doi.org/10.1155/2014/193925 |
| spellingShingle | Anu Priyadharshini Srinivasan B. O. Parijatham Omprakash Kandhimalla Lavanya Priyadharshini Subbulakshmi Murugesan Saraswathi Kandaswamy A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies Journal of Pregnancy |
| title | A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies |
| title_full | A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies |
| title_fullStr | A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies |
| title_full_unstemmed | A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies |
| title_short | A Prospective Study of Villous Capillary Lesions in Complicated Pregnancies |
| title_sort | prospective study of villous capillary lesions in complicated pregnancies |
| url | http://dx.doi.org/10.1155/2014/193925 |
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