Comparison of the Effects of Intrathecal Fentanyl and Intrathecal Morphine on Pain in Elective Total Knee Replacement Surgery
Objective. Total knee replacement is one of the most painful orthopedic surgical procedures. In this study, our goal was to compare the intraoperative and postoperative hemodynamic effects, the side effects, the effect on the duration of pain start, the 24-hour VAS, and the amount of additional anal...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2016/3256583 |
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| author | Refika Kılıçkaya Yavuz Orak Mehtap Arda Balcı Fatih Balcı İlker Ünal |
| author_facet | Refika Kılıçkaya Yavuz Orak Mehtap Arda Balcı Fatih Balcı İlker Ünal |
| author_sort | Refika Kılıçkaya |
| collection | DOAJ |
| description | Objective. Total knee replacement is one of the most painful orthopedic surgical procedures. In this study, our goal was to compare the intraoperative and postoperative hemodynamic effects, the side effects, the effect on the duration of pain start, the 24-hour VAS, and the amount of additional analgesia used, of the fentanyl and morphine we added to the local anesthetic in the spinal anesthesia we administered in cases of elective knee replacement. Materials and Methods. After obtaining the approval of the Erciyes University Medical Faculty Clinical Drug Trials Ethics Committee, as well as the verbal and written consent of the patients, we included 50 patients in our prospective, randomized study. Results. In our study, the morphine group (Group M) had lower pain scores in the 2nd, 6th, 12th, and 24th hours compared to the fentanyl group (Group F). When additional analgesic requirements were compared, it was found that in the 2nd, 6th, and 24th hours fewer Group M patients needed more analgesics than did Group F patients. Conclusion. The fentanyl group also had lower first analgesic requirement times than did the morphine group. In terms of nausea and vomiting, there was no statistically significant difference between the two groups. |
| format | Article |
| id | doaj-art-19b1331582b4435492bd0113c15752cc |
| institution | Kabale University |
| issn | 1203-6765 1918-1523 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-19b1331582b4435492bd0113c15752cc2025-02-03T01:10:11ZengWileyPain Research and Management1203-67651918-15232016-01-01201610.1155/2016/32565833256583Comparison of the Effects of Intrathecal Fentanyl and Intrathecal Morphine on Pain in Elective Total Knee Replacement SurgeryRefika Kılıçkaya0Yavuz Orak1Mehtap Arda Balcı2Fatih Balcı3İlker Ünal4Anesthesiology and Reanimation Clinic, Bor State Hospital, Niğde, TurkeyAnesthesiology and Reanimation Clinic, Mardin State Hospital, Mardin, TurkeyAnesthesiology and Reanimation Clinic, Bor State Hospital, Niğde, TurkeyAnesthesiology and Reanimation Clinic, Niğde State Hospital, Niğde, TurkeyMedical Biostatistics Department, Çukurova University, Adana, TurkeyObjective. Total knee replacement is one of the most painful orthopedic surgical procedures. In this study, our goal was to compare the intraoperative and postoperative hemodynamic effects, the side effects, the effect on the duration of pain start, the 24-hour VAS, and the amount of additional analgesia used, of the fentanyl and morphine we added to the local anesthetic in the spinal anesthesia we administered in cases of elective knee replacement. Materials and Methods. After obtaining the approval of the Erciyes University Medical Faculty Clinical Drug Trials Ethics Committee, as well as the verbal and written consent of the patients, we included 50 patients in our prospective, randomized study. Results. In our study, the morphine group (Group M) had lower pain scores in the 2nd, 6th, 12th, and 24th hours compared to the fentanyl group (Group F). When additional analgesic requirements were compared, it was found that in the 2nd, 6th, and 24th hours fewer Group M patients needed more analgesics than did Group F patients. Conclusion. The fentanyl group also had lower first analgesic requirement times than did the morphine group. In terms of nausea and vomiting, there was no statistically significant difference between the two groups.http://dx.doi.org/10.1155/2016/3256583 |
| spellingShingle | Refika Kılıçkaya Yavuz Orak Mehtap Arda Balcı Fatih Balcı İlker Ünal Comparison of the Effects of Intrathecal Fentanyl and Intrathecal Morphine on Pain in Elective Total Knee Replacement Surgery Pain Research and Management |
| title | Comparison of the Effects of Intrathecal Fentanyl and Intrathecal Morphine on Pain in Elective Total Knee Replacement Surgery |
| title_full | Comparison of the Effects of Intrathecal Fentanyl and Intrathecal Morphine on Pain in Elective Total Knee Replacement Surgery |
| title_fullStr | Comparison of the Effects of Intrathecal Fentanyl and Intrathecal Morphine on Pain in Elective Total Knee Replacement Surgery |
| title_full_unstemmed | Comparison of the Effects of Intrathecal Fentanyl and Intrathecal Morphine on Pain in Elective Total Knee Replacement Surgery |
| title_short | Comparison of the Effects of Intrathecal Fentanyl and Intrathecal Morphine on Pain in Elective Total Knee Replacement Surgery |
| title_sort | comparison of the effects of intrathecal fentanyl and intrathecal morphine on pain in elective total knee replacement surgery |
| url | http://dx.doi.org/10.1155/2016/3256583 |
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