Influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis
The main objective of this study was to evaluate the influence of the formulation and process parameters on PLGA microparticles containing a practically insoluble model drug (ibuprofen) prepared by the o/w solvent evaporation method. Multivariate data analysis was used. The effects of altered stirri...
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Main Authors: | Vysloužil Jakub, Doležel Petr, Kejdušová Martina, Mašková Eliška, Mašek Josef, Lukáč Robert, Košťál Vratislav, Vetchý David, Dvořáčková Kateřina |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2014-12-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2014-0032 |
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