Rat Bite Fever Resembling Rheumatoid Arthritis

Rat bite fever is rare in Western countries. It can be very difficult to diagnose as blood cultures are typically negative and a history of rodent exposure is often missed. Unless a high index of suspicion is maintained, the associated polyarthritis can be mistaken for rheumatoid arthritis. We repor...

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Main Authors: Ripa Akter, Paul Boland, Peter Daley, Proton Rahman, Nayef Al Ghanim
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2016/7270413
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author Ripa Akter
Paul Boland
Peter Daley
Proton Rahman
Nayef Al Ghanim
author_facet Ripa Akter
Paul Boland
Peter Daley
Proton Rahman
Nayef Al Ghanim
author_sort Ripa Akter
collection DOAJ
description Rat bite fever is rare in Western countries. It can be very difficult to diagnose as blood cultures are typically negative and a history of rodent exposure is often missed. Unless a high index of suspicion is maintained, the associated polyarthritis can be mistaken for rheumatoid arthritis. We report a case of culture-positive rat bite fever in a 46-year-old female presenting with fever and polyarthritis. The clinical presentation mimicked rheumatoid arthritis. Infection was complicated by discitis, a rare manifestation. We discuss the diagnosis and management of this rare zoonotic infection. We also review nine reported cases of rat bite fever, all of which had an initial presumptive diagnosis of a rheumatological disorder. Rat bite fever is a potentially curable infection but can have a lethal course if left untreated.
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institution Kabale University
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language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-19ab8c6c767543b4883d1f3002b665a82025-02-03T05:45:32ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932016-01-01201610.1155/2016/72704137270413Rat Bite Fever Resembling Rheumatoid ArthritisRipa Akter0Paul Boland1Peter Daley2Proton Rahman3Nayef Al Ghanim4Department of Internal Medicine, Memorial University, St. John’s, NL, A1B 3V6, CanadaDepartment of Internal Medicine, Memorial University, St. John’s, NL, A1B 3V6, CanadaDisciplines of Medicine and Laboratory Medicine, Memorial University, St. John’s, NL, A1B 3V6, CanadaDepartment of Medicine, Memorial University, St. John’s, NL, A1B 3V6, CanadaEastern Health, St. John’s, NL, A1C 5B8, CanadaRat bite fever is rare in Western countries. It can be very difficult to diagnose as blood cultures are typically negative and a history of rodent exposure is often missed. Unless a high index of suspicion is maintained, the associated polyarthritis can be mistaken for rheumatoid arthritis. We report a case of culture-positive rat bite fever in a 46-year-old female presenting with fever and polyarthritis. The clinical presentation mimicked rheumatoid arthritis. Infection was complicated by discitis, a rare manifestation. We discuss the diagnosis and management of this rare zoonotic infection. We also review nine reported cases of rat bite fever, all of which had an initial presumptive diagnosis of a rheumatological disorder. Rat bite fever is a potentially curable infection but can have a lethal course if left untreated.http://dx.doi.org/10.1155/2016/7270413
spellingShingle Ripa Akter
Paul Boland
Peter Daley
Proton Rahman
Nayef Al Ghanim
Rat Bite Fever Resembling Rheumatoid Arthritis
Canadian Journal of Infectious Diseases and Medical Microbiology
title Rat Bite Fever Resembling Rheumatoid Arthritis
title_full Rat Bite Fever Resembling Rheumatoid Arthritis
title_fullStr Rat Bite Fever Resembling Rheumatoid Arthritis
title_full_unstemmed Rat Bite Fever Resembling Rheumatoid Arthritis
title_short Rat Bite Fever Resembling Rheumatoid Arthritis
title_sort rat bite fever resembling rheumatoid arthritis
url http://dx.doi.org/10.1155/2016/7270413
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AT paulboland ratbitefeverresemblingrheumatoidarthritis
AT peterdaley ratbitefeverresemblingrheumatoidarthritis
AT protonrahman ratbitefeverresemblingrheumatoidarthritis
AT nayefalghanim ratbitefeverresemblingrheumatoidarthritis