Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the Lungs
Myoepithelial carcinoma is an uncommon tumor of the salivary glands, most commonly the parotid gland. Clear cell myoepithelial carcinoma is a rare variant with an aggressive behavior. Here, we describe a case of clear cell myoepithelial carcinoma arising from the hard palate in an elderly male who u...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2019/3863270 |
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| author | Jiayun Fang Amanda Kornfield Alex Clavijo Shikhar Vyas Alison Ulbrandt Carsten Schroeder J. Kenneth Byrd Daniel Kleven |
| author_facet | Jiayun Fang Amanda Kornfield Alex Clavijo Shikhar Vyas Alison Ulbrandt Carsten Schroeder J. Kenneth Byrd Daniel Kleven |
| author_sort | Jiayun Fang |
| collection | DOAJ |
| description | Myoepithelial carcinoma is an uncommon tumor of the salivary glands, most commonly the parotid gland. Clear cell myoepithelial carcinoma is a rare variant with an aggressive behavior. Here, we describe a case of clear cell myoepithelial carcinoma arising from the hard palate in an elderly male who underwent resection of the tumor and postop radiation. Posttreatment imaging demonstrated bilateral pulmonary nodules and a C2 body lesion concerning for metastasis. Biopsy of the lung lesions revealed a monomorphous population of optically clear cells with hyperchromatic and pleomorphic nuclei which were morphologically similar to the prior resection specimen. There are few reported cases of clear cell myoepithelial carcinoma arising from the hard palate, and there are even fewer reports on metastases to the lungs. Due to the low number of reported cases, prognosis and treatment of this neoplasm is not well defined. |
| format | Article |
| id | doaj-art-19509869206048e38e4e04de106f9cf0 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-19509869206048e38e4e04de106f9cf02025-02-03T00:59:17ZengWileyCase Reports in Pathology2090-67812090-679X2019-01-01201910.1155/2019/38632703863270Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the LungsJiayun Fang0Amanda Kornfield1Alex Clavijo2Shikhar Vyas3Alison Ulbrandt4Carsten Schroeder5J. Kenneth Byrd6Daniel Kleven7School of Medicine at Medical College of Georgia at Augusta University, Augusta, GA, USASchool of Medicine at Medical College of Georgia at Augusta University, Augusta, GA, USADepartment of Pathology at Medical College of Georgia at Augusta University, Augusta, GA, USADepartment of Pathology at Medical College of Georgia at Augusta University, Augusta, GA, USADepartment of Radiology at Medical College of Georgia at Augusta University, Augusta, GA, USADepartment of Thoracic Oncology Surgery at Medical College of Georgia at Augusta University, Augusta, GA, USADepartment of Head and Neck Surgery at Medical College of Georgia at Augusta University, Augusta, GA, USADepartment of Pathology at Medical College of Georgia at Augusta University, Augusta, GA, USAMyoepithelial carcinoma is an uncommon tumor of the salivary glands, most commonly the parotid gland. Clear cell myoepithelial carcinoma is a rare variant with an aggressive behavior. Here, we describe a case of clear cell myoepithelial carcinoma arising from the hard palate in an elderly male who underwent resection of the tumor and postop radiation. Posttreatment imaging demonstrated bilateral pulmonary nodules and a C2 body lesion concerning for metastasis. Biopsy of the lung lesions revealed a monomorphous population of optically clear cells with hyperchromatic and pleomorphic nuclei which were morphologically similar to the prior resection specimen. There are few reported cases of clear cell myoepithelial carcinoma arising from the hard palate, and there are even fewer reports on metastases to the lungs. Due to the low number of reported cases, prognosis and treatment of this neoplasm is not well defined.http://dx.doi.org/10.1155/2019/3863270 |
| spellingShingle | Jiayun Fang Amanda Kornfield Alex Clavijo Shikhar Vyas Alison Ulbrandt Carsten Schroeder J. Kenneth Byrd Daniel Kleven Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the Lungs Case Reports in Pathology |
| title | Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the Lungs |
| title_full | Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the Lungs |
| title_fullStr | Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the Lungs |
| title_full_unstemmed | Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the Lungs |
| title_short | Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the Lungs |
| title_sort | clear cell myoepithelial carcinoma arising from the hard palate with metastasis to the lungs |
| url | http://dx.doi.org/10.1155/2019/3863270 |
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