Glucagon-like peptide-1 receptor modulates cerebrospinal fluid secretion and intracranial pressure in rats

Glucagon-like peptide-1 receptor modulates cerebrospinal fluid secretion and intracranial pressure in rats

Abstract Background Cerebrospinal fluid (CSF) is produced and absorbed at a balanced rate to maintain a constant intracranial pressure (ICP). The CSF dynamics are, however, disturbed in several pathological conditions, leading to elevated ICP, which may have fatal outcomes if left untreated. Treatme...

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Bibliographic Details
Main Authors: Mette N. Jensen, Ida M. E. Israelsen, Jonathan H. Wardman, Dennis B. Jensen, Daniel B. Andersen, Trine L. Toft-Bertelsen, Martin F. Rath, Jens Juul Holst, Mette M. Rosenkilde, Nanna MacAulay
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Fluids and Barriers of the CNS
Subjects:
GLP-1
ICP
CSF
Choroid plexus
Hydrocephalus
IIH
Online Access:https://doi.org/10.1186/s12987-025-00652-x
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