Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation

BACKGROUND: Liver transplantation (LT) offers a possible cure for patients with hepatocellular carcinoma (HCC) and cirrhosis. However, tumour progression while on the waiting list and tumour recurrence after LT are common. The prognostic significance of various pre- and postoperative variables were...

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Main Authors: Kathy Han, George N Tzimas, Jeffrey S Barkun, Peter Metrakos, Jean I Tchervenkov, Nir Hilzenrat, Phil Wong, M Deschênes
Format: Article
Language:English
Published: Wiley 2007-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2007/206383
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author Kathy Han
George N Tzimas
Jeffrey S Barkun
Peter Metrakos
Jean I Tchervenkov
Nir Hilzenrat
Phil Wong
M Deschênes
author_facet Kathy Han
George N Tzimas
Jeffrey S Barkun
Peter Metrakos
Jean I Tchervenkov
Nir Hilzenrat
Phil Wong
M Deschênes
author_sort Kathy Han
collection DOAJ
description BACKGROUND: Liver transplantation (LT) offers a possible cure for patients with hepatocellular carcinoma (HCC) and cirrhosis. However, tumour progression while on the waiting list and tumour recurrence after LT are common. The prognostic significance of various pre- and postoperative variables were investigated in regard to tumour recurrence, with an emphasis on the slope of preoperative serum alpha-fetoprotein (AFP) levels.
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institution Kabale University
issn 0835-7900
language English
publishDate 2007-01-01
publisher Wiley
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series Canadian Journal of Gastroenterology
spelling doaj-art-1946c4085610454dbbe641f9b34fd0322025-02-03T06:44:22ZengWileyCanadian Journal of Gastroenterology0835-79002007-01-01211394510.1155/2007/206383Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver TransplantationKathy Han0George N Tzimas1Jeffrey S Barkun2Peter Metrakos3Jean I Tchervenkov4Nir Hilzenrat5Phil Wong6M Deschênes7Liver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaLiver Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, CanadaBACKGROUND: Liver transplantation (LT) offers a possible cure for patients with hepatocellular carcinoma (HCC) and cirrhosis. However, tumour progression while on the waiting list and tumour recurrence after LT are common. The prognostic significance of various pre- and postoperative variables were investigated in regard to tumour recurrence, with an emphasis on the slope of preoperative serum alpha-fetoprotein (AFP) levels.http://dx.doi.org/10.1155/2007/206383
spellingShingle Kathy Han
George N Tzimas
Jeffrey S Barkun
Peter Metrakos
Jean I Tchervenkov
Nir Hilzenrat
Phil Wong
M Deschênes
Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
Canadian Journal of Gastroenterology
title Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_full Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_fullStr Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_full_unstemmed Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_short Preoperative Alpha-Fetoprotein Slope is Predictive of Hepatocellular Carcinoma Recurrence after Liver Transplantation
title_sort preoperative alpha fetoprotein slope is predictive of hepatocellular carcinoma recurrence after liver transplantation
url http://dx.doi.org/10.1155/2007/206383
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