The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a complicated disease involving multiple pathogenic factors. The complex relationships between long-chain fatty acids (LCFAs) and the morbidity of IBD drive numerous studies to unravel the underlying mechanisms. A better understanding of the role of LCFAs in IBD w...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2019/8495913 |
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| _version_ | 1832546509734805504 |
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| author | Chunxiang Ma Reshma Vasu Hu Zhang |
| author_facet | Chunxiang Ma Reshma Vasu Hu Zhang |
| author_sort | Chunxiang Ma |
| collection | DOAJ |
| description | Inflammatory bowel disease (IBD) is a complicated disease involving multiple pathogenic factors. The complex relationships between long-chain fatty acids (LCFAs) and the morbidity of IBD drive numerous studies to unravel the underlying mechanisms. A better understanding of the role of LCFAs in IBD will substitute or boost the current IBD therapies, thereby obtaining mucosal healing. In this review, we focused on the roles of LCFAs on the important links of inflammatory regulation in IBD, including in the pathogen recognition phase and in the inflammatory resolving phase, and the effects of LCFAs on immune cells in IBD. |
| format | Article |
| id | doaj-art-193d1bd52cd042518817c89f32a0def1 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-193d1bd52cd042518817c89f32a0def12025-02-03T06:48:08ZengWileyMediators of Inflammation0962-93511466-18612019-01-01201910.1155/2019/84959138495913The Role of Long-Chain Fatty Acids in Inflammatory Bowel DiseaseChunxiang Ma0Reshma Vasu1Hu Zhang2Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, ChinaWest China School of Medicine, Sichuan University, Chengdu, ChinaDepartment of Gastroenterology, West China Hospital, Sichuan University, Chengdu, ChinaInflammatory bowel disease (IBD) is a complicated disease involving multiple pathogenic factors. The complex relationships between long-chain fatty acids (LCFAs) and the morbidity of IBD drive numerous studies to unravel the underlying mechanisms. A better understanding of the role of LCFAs in IBD will substitute or boost the current IBD therapies, thereby obtaining mucosal healing. In this review, we focused on the roles of LCFAs on the important links of inflammatory regulation in IBD, including in the pathogen recognition phase and in the inflammatory resolving phase, and the effects of LCFAs on immune cells in IBD.http://dx.doi.org/10.1155/2019/8495913 |
| spellingShingle | Chunxiang Ma Reshma Vasu Hu Zhang The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease Mediators of Inflammation |
| title | The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease |
| title_full | The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease |
| title_fullStr | The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease |
| title_full_unstemmed | The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease |
| title_short | The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease |
| title_sort | role of long chain fatty acids in inflammatory bowel disease |
| url | http://dx.doi.org/10.1155/2019/8495913 |
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