Peripheral nerve regeneration using a bioresorbable silk fibroin-based artificial nerve conduit fabricated via a novel freeze–thaw process

Peripheral nerve regeneration using a bioresorbable silk fibroin-based artificial nerve conduit fabricated via a novel freeze–thaw process

Abstract While silk fibroin (SF) obtained from silkworm cocoons is expected to become a next-generation natural polymer, a fabrication method for SF-based artificial nerve conduits (SFCs) has not yet been established. Here, we report a bioresorbable SFC, fabricated using a novel freeze–thaw process,...

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Bibliographic Details
Main Authors: Tomoki Matsuo, Hiroo Kimura, Takayuki Nishijima, Yasuhiro Kiyota, Taku Suzuki, Narihito Nagoshi, Shinsuke Shibata, Tomoko Shindo, Nobuko Moritoki, Makoto Sasaki, Sarara Noguchi, Yasushi Tamada, Masaya Nakamura, Takuji Iwamoto
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Silk fibroin
Nerve conduit
Artificial nerve
Scaffold
Peripheral nerve injury
Nerve regeneration
Online Access:https://doi.org/10.1038/s41598-025-88221-y
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