Alflutop clinical efficacy in vertebral osteochondrosis (12-mohth study)
Objective. To study clinical efficacy of aiflutop (A) in lumbar osteochondrosis (LO) with chronic back pain syndrome. Material and Methods. 32 pts with LO were included. 14 from them (group 1) during a year received 2 courses of A intramuscular injections (I ml/day, 30 ml total) and nonsteroidal ant...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA PRESS LLC
2005-04-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/1328 |
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| Summary: | Objective. To study clinical efficacy of aiflutop (A) in lumbar osteochondrosis (LO) with chronic back pain syndrome. Material and Methods. 32 pts with LO were included. 14 from them (group 1) during a year received 2 courses of A intramuscular injections (I ml/day, 30 ml total) and nonsteroidal anti-inflammatory drugs (NSAIDs) if necessary. 18 pts (group 2) received NSAIDs only. Clinical examination of pts was performed at the stert of the study, before and after each A course and in 3 months after the last course. Results. Pain in the spine at rest and forward bending significantly decreased in group 1 pts (p<0,05) after each A course. Full pain disappearance after the first A course was achieved in 7,1% and after the second course - in 35,7% of group I pts and was not shown in control group. Significant stepped decrease of Thomayer's test value (p<0,00l) was also shown in group 1: 3,6 times decrease in comparison with baseline was achieved in 3 months after completion of treatment with A. During treatment period these pts showed 2-2,5 times increase of static and dynamic spine load (according to Vxdel chronic inability index). 42,9% of group I pts stopped NSAIDs after A treatment completion. Only 5,6% of control group pts stopped NSAIDs during follow up. A tolerability was good. It can be combined with any other medications the pts received due to comorbid diseases. |
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| ISSN: | 1995-4484 1995-4492 |