Construction of Trans-4-hydroxy-L-proline-producing <i>Escherichia coli</i> and Optimization of Fermentation Conditions

In this study, we combined the citric acid cycle with the biosynthesis pathways of L-proline and L-hydroxyproline to construct a strain that produces L-hydroxyproline directly from glucose and other raw materials, without the addition of L-proline and α-ketoglutarate. The results showed that the lev...

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Bibliographic Details
Main Authors: Xinchao Yang, Xinyu Li, Yuanxiu Wang, Yuehui Liu, Fang Wang, Naxin Sun, Chunjiang Ye
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Fermentation
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Online Access:https://www.mdpi.com/2311-5637/11/2/54
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