Origami with small molecules: exploiting the C–F bond as a conformational tool

When present within an organic molecule, the C–F bond tends to align in predictable ways with neighbouring functional groups, due to stereoelectronic effects such as hyperconjugation and electrostatic attraction/repulsion. These fluorine-derived conformational effects have been exploited to control...

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Bibliographic Details
Main Authors: Patrick Ryan, Ramsha Iftikhar, Luke Hunter
Format: Article
Language:English
Published: Beilstein-Institut 2025-04-01
Series:Beilstein Journal of Organic Chemistry
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Online Access:https://doi.org/10.3762/bjoc.21.54
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