Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazone
Transition metal complexes of Cr(III), Fe(III), Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) with a tridentate ligand, 4-hydroxy-4-methyl-2-pentanone-1H-benzimidazole-2yl-hydrazone (H-HPBH) derived from the condensation of 2-hydrazinobenzimidazole and diacetone alcohol was synthesized. Characterization...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2011/323404 |
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| author | M. Neelamma P. Venkateswar Rao G. H. Anuradha |
| author_facet | M. Neelamma P. Venkateswar Rao G. H. Anuradha |
| author_sort | M. Neelamma |
| collection | DOAJ |
| description | Transition metal complexes of Cr(III), Fe(III), Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) with a tridentate ligand, 4-hydroxy-4-methyl-2-pentanone-1H-benzimidazole-2yl-hydrazone (H-HPBH) derived from the condensation of 2-hydrazinobenzimidazole and diacetone alcohol was synthesized. Characterization has been done on the basis of analytical, conductance, thermal and magnetic data, infrared, 1H NMR, electronic, mass and ESR spectral data. From analytical and thermal data, the stoichiometry of the complexes has been found to be 1:1 (metal: ligand). Divalent complexes have the general formula [M(HPBH)Cl(H2O)2] in octahedral geometry, [M(HPBH)Cl] in tetrahedral and square planar stereochemistries and trivalent complexes [M(HPBH)Cl2(H2O)] in octahedral disposition. Infrared spectral data suggest that the ligand HPBH behaves as a monobasic tridentate ligand with N: N: O donor sequence towards the metal ions. On the basis of the above physicochemical data, octahedral, tetrahedral and square planar geometries were assigned for the complexes. The ligand and metal complexes were screened for their physiological activities against E. coli and S. aureus. The order of physiological activity has been found to be Cu(II) > Ni(II) > Zn(II) > Co(II) > Cr(III) > Mn(II) > Fe (III) > ligand against E.coli and Ni(II) > Cu(II) > Zn(II) > Mn(II) > Cr(III) > Fe(III) > Co(II) > ligand against S. aureus. |
| format | Article |
| id | doaj-art-18e1e1299ab54e5a95c36809ee8121e4 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-18e1e1299ab54e5a95c36809ee8121e42025-02-03T06:00:04ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-0181293610.1155/2011/323404Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazoneM. Neelamma0P. Venkateswar Rao1G. H. Anuradha2Department of Chemistry, R B V R Reddy Women's College Narayanguda, Hyderabad-500029, IndiaDepartment of Chemistry, Nizam College, Hyderabad-500001, IndiaDepartment of Chemistry, R B V R Reddy Women's College Narayanguda, Hyderabad-500029, IndiaTransition metal complexes of Cr(III), Fe(III), Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) with a tridentate ligand, 4-hydroxy-4-methyl-2-pentanone-1H-benzimidazole-2yl-hydrazone (H-HPBH) derived from the condensation of 2-hydrazinobenzimidazole and diacetone alcohol was synthesized. Characterization has been done on the basis of analytical, conductance, thermal and magnetic data, infrared, 1H NMR, electronic, mass and ESR spectral data. From analytical and thermal data, the stoichiometry of the complexes has been found to be 1:1 (metal: ligand). Divalent complexes have the general formula [M(HPBH)Cl(H2O)2] in octahedral geometry, [M(HPBH)Cl] in tetrahedral and square planar stereochemistries and trivalent complexes [M(HPBH)Cl2(H2O)] in octahedral disposition. Infrared spectral data suggest that the ligand HPBH behaves as a monobasic tridentate ligand with N: N: O donor sequence towards the metal ions. On the basis of the above physicochemical data, octahedral, tetrahedral and square planar geometries were assigned for the complexes. The ligand and metal complexes were screened for their physiological activities against E. coli and S. aureus. The order of physiological activity has been found to be Cu(II) > Ni(II) > Zn(II) > Co(II) > Cr(III) > Mn(II) > Fe (III) > ligand against E.coli and Ni(II) > Cu(II) > Zn(II) > Mn(II) > Cr(III) > Fe(III) > Co(II) > ligand against S. aureus.http://dx.doi.org/10.1155/2011/323404 |
| spellingShingle | M. Neelamma P. Venkateswar Rao G. H. Anuradha Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazone E-Journal of Chemistry |
| title | Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazone |
| title_full | Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazone |
| title_fullStr | Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazone |
| title_full_unstemmed | Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazone |
| title_short | Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazone |
| title_sort | synthesis and structural studies on transition metal complexes derived from 4 hydroxy 4 methyl 2 pentanone 1h benzimidazol 2 yl hydrazone |
| url | http://dx.doi.org/10.1155/2011/323404 |
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