Transient Peripapillary Retinoschisis in Glaucomatous Eyes
Purpose. To investigate transient focal microcystic retinoschisis in glaucomatous eyes in images obtained with several imaging techniques used in daily glaucoma care. Methods. Images of 117 glaucoma patients and 91 healthy subjects participating in a large prospective follow-up study into glaucoma i...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/1536030 |
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| author | Josine van der Schoot Koenraad A. Vermeer Hans G. Lemij |
| author_facet | Josine van der Schoot Koenraad A. Vermeer Hans G. Lemij |
| author_sort | Josine van der Schoot |
| collection | DOAJ |
| description | Purpose. To investigate transient focal microcystic retinoschisis in glaucomatous eyes in images obtained with several imaging techniques used in daily glaucoma care. Methods. Images of 117 glaucoma patients and 91 healthy subjects participating in a large prospective follow-up study into glaucoma imaging were reviewed. Participants were measured with spectral domain optical coherence tomography (SD-OCT), scanning laser polarimetry (SLP), scanning laser tomography (SLT), and standard automated perimetry (SAP). The presence of a focal retinoschisis in SD-OCT was observed and correlated to SLP, SLT, and SAP measurements, both cross-sectionally and longitudinally. Results. Seven out of 117 glaucoma patients showed a transient, localised, peripapillary, heterogeneous microcystic schisis of the retinal nerve fiber layer (RNFL) and sometimes other retinal layers as well in SD-OCT. None of the healthy eyes showed this phenomenon nor did any of the other imaging techniques display it as detailed and consistently as did the SD-OCT. SAP showed a temporarily decreased focal retinal sensitivity during the retinoschisis and we found no signs of glaucomatous progression related to the retinoschisis. Conclusions. Transient microcystic retinoschisis appears to be associated with glaucomatous wedge defects in the RNFL. It was best observed with SD-OCT and it was absent in healthy eyes. We found no evidence that the retinoschisis predicted glaucomatous progression. |
| format | Article |
| id | doaj-art-18c47dc0b21544d7b538d06ebf778787 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-18c47dc0b21544d7b538d06ebf7787872025-02-03T01:32:40ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/15360301536030Transient Peripapillary Retinoschisis in Glaucomatous EyesJosine van der Schoot0Koenraad A. Vermeer1Hans G. Lemij2Rotterdam Ophthalmic Institute, The Rotterdam Eye Hospital, Rotterdam, NetherlandsRotterdam Ophthalmic Institute, The Rotterdam Eye Hospital, Rotterdam, NetherlandsGlaucoma Service, The Rotterdam Eye Hospital, Rotterdam, NetherlandsPurpose. To investigate transient focal microcystic retinoschisis in glaucomatous eyes in images obtained with several imaging techniques used in daily glaucoma care. Methods. Images of 117 glaucoma patients and 91 healthy subjects participating in a large prospective follow-up study into glaucoma imaging were reviewed. Participants were measured with spectral domain optical coherence tomography (SD-OCT), scanning laser polarimetry (SLP), scanning laser tomography (SLT), and standard automated perimetry (SAP). The presence of a focal retinoschisis in SD-OCT was observed and correlated to SLP, SLT, and SAP measurements, both cross-sectionally and longitudinally. Results. Seven out of 117 glaucoma patients showed a transient, localised, peripapillary, heterogeneous microcystic schisis of the retinal nerve fiber layer (RNFL) and sometimes other retinal layers as well in SD-OCT. None of the healthy eyes showed this phenomenon nor did any of the other imaging techniques display it as detailed and consistently as did the SD-OCT. SAP showed a temporarily decreased focal retinal sensitivity during the retinoschisis and we found no signs of glaucomatous progression related to the retinoschisis. Conclusions. Transient microcystic retinoschisis appears to be associated with glaucomatous wedge defects in the RNFL. It was best observed with SD-OCT and it was absent in healthy eyes. We found no evidence that the retinoschisis predicted glaucomatous progression.http://dx.doi.org/10.1155/2017/1536030 |
| spellingShingle | Josine van der Schoot Koenraad A. Vermeer Hans G. Lemij Transient Peripapillary Retinoschisis in Glaucomatous Eyes Journal of Ophthalmology |
| title | Transient Peripapillary Retinoschisis in Glaucomatous Eyes |
| title_full | Transient Peripapillary Retinoschisis in Glaucomatous Eyes |
| title_fullStr | Transient Peripapillary Retinoschisis in Glaucomatous Eyes |
| title_full_unstemmed | Transient Peripapillary Retinoschisis in Glaucomatous Eyes |
| title_short | Transient Peripapillary Retinoschisis in Glaucomatous Eyes |
| title_sort | transient peripapillary retinoschisis in glaucomatous eyes |
| url | http://dx.doi.org/10.1155/2017/1536030 |
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