Empowering hypoxia to convert cold tumors into hot tumors for breast cancer immunotherapy

Abstract Breast cancer remains the most common cancer among women globally and a leading cause of cancer-related death. Despite the promise of immunotherapy for triple-negative breast cancer (TNBC), its overall effectiveness is hindered by the cold tumor microenvironment (TME), characterized by spar...

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Bibliographic Details
Main Authors: Lu Liu, Danping Wu, Zhiwen Qian, Ying Jiang, Yilan You, YiDa Wang, Feng Zhang, Xin Ning, Jie Mei, Jabed Iqbal, Yanfang Gu, Yan Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02682-8
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