Evolution of uncontrolled proliferation and the angiogenic switch in cancer

The major goal of evolutionary oncology is to explain how malignant traits evolve to become cancer 'hallmarks.' One such hallmark---the angiogenic switch---is difficult to explain for the same reason altruism is difficult to explain. An angiogenic clone is vulnerable to 'cheater'...

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Bibliographic Details
Main Authors: John D. Nagy, Dieter Armbruster
Format: Article
Language:English
Published: AIMS Press 2012-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.843
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