Evolution of uncontrolled proliferation and the angiogenic switch in cancer
The major goal of evolutionary oncology is to explain how malignant traits evolve to become cancer 'hallmarks.' One such hallmark---the angiogenic switch---is difficult to explain for the same reason altruism is difficult to explain. An angiogenic clone is vulnerable to 'cheater'...
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Main Authors: | John D. Nagy, Dieter Armbruster |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2012-09-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.843 |
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