Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets

Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets

ObjectiveThis study aims to identify potential target genes and therapeutic drugs for alopecia areata (AA).MethodsUtilizing training and testing data, we evaluated multi-gene panels derived from commonly upregulated genes in publicly available AA patient datasets. The functions of these genes in bio...

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Bibliographic Details
Main Authors: Hongye Liu, Yang Li, Ling Ren, Xiaofeng Yang, Shuo Zhang, Hongmei Bi, Hongxia He, Jingyu Ren, Xiaoqing Lang, Shuping Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Physiology
Subjects:
immune cell infiltration
multi-gene panel
alopecia areata
machine learning
module eigen genes
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1489907/full
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