Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations
This paper reports the case of a 27-year-old man with paranoid schizophrenia who was finally stabilized on clozapine medication. After vaccination against severe acute respiratory syndrome coronavirus 2, serum levels of clozapine increased. It is well established that immune responses can trigger cy...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-01-01
|
| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2023/9914879 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559606797172736 |
|---|---|
| author | Xenia A. K. Kersting Nicoletta Momtahen Klaus Lieb |
| author_facet | Xenia A. K. Kersting Nicoletta Momtahen Klaus Lieb |
| author_sort | Xenia A. K. Kersting |
| collection | DOAJ |
| description | This paper reports the case of a 27-year-old man with paranoid schizophrenia who was finally stabilized on clozapine medication. After vaccination against severe acute respiratory syndrome coronavirus 2, serum levels of clozapine increased. It is well established that immune responses can trigger cytokine cascades affecting drug metabolism, which, in the case of clozapine treatment, can lead to severe intoxication. |
| format | Article |
| id | doaj-art-1808154c0cb440e29c311d6069715b32 |
| institution | Kabale University |
| issn | 2090-6838 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-1808154c0cb440e29c311d6069715b322025-02-03T01:29:35ZengWileyCase Reports in Psychiatry2090-68382023-01-01202310.1155/2023/9914879Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 VaccinationsXenia A. K. Kersting0Nicoletta Momtahen1Klaus Lieb2Department of Psychiatry and PsychotherapyDepartment of Psychiatry and PsychotherapyDepartment of Psychiatry and PsychotherapyThis paper reports the case of a 27-year-old man with paranoid schizophrenia who was finally stabilized on clozapine medication. After vaccination against severe acute respiratory syndrome coronavirus 2, serum levels of clozapine increased. It is well established that immune responses can trigger cytokine cascades affecting drug metabolism, which, in the case of clozapine treatment, can lead to severe intoxication.http://dx.doi.org/10.1155/2023/9914879 |
| spellingShingle | Xenia A. K. Kersting Nicoletta Momtahen Klaus Lieb Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations Case Reports in Psychiatry |
| title | Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations |
| title_full | Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations |
| title_fullStr | Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations |
| title_full_unstemmed | Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations |
| title_short | Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations |
| title_sort | clozapine serum concentrations are disrupted by sars cov 2 vaccinations |
| url | http://dx.doi.org/10.1155/2023/9914879 |
| work_keys_str_mv | AT xeniaakkersting clozapineserumconcentrationsaredisruptedbysarscov2vaccinations AT nicolettamomtahen clozapineserumconcentrationsaredisruptedbysarscov2vaccinations AT klauslieb clozapineserumconcentrationsaredisruptedbysarscov2vaccinations |