X-Mapper: fast and accurate sequence alignment via gapped x-mers
Abstract Sequence alignment is foundational to many bioinformatic analyses. Many aligners start by splitting sequences into contiguous, fixed-length seeds, called k-mers. Alignment is faster with longer, unique seeds, but more accurate with shorter seeds avoiding mutations. Here, we introduce X-Mapp...
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Main Authors: | Jeffry M. Gaston, Eric J. Alm, An-Ni Zhang |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-024-03473-7 |
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