Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy

A 71-year-old woman collapsed while working as a grocery store cashier. CPR was performed and an AED revealed torsades de pointes (TdP). She was subsequently defibrillated resulting in restoration of sinus rhythm with a QTc interval of 544 msec. Further evaluation revealed a diagnosis of Takotsubo C...

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Main Authors: Michael Gysel, Alexander Crystal, Jules C. Hancox, Michelle Methot, Adrian Baranchuk
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2014/213842
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author Michael Gysel
Alexander Crystal
Jules C. Hancox
Michelle Methot
Adrian Baranchuk
author_facet Michael Gysel
Alexander Crystal
Jules C. Hancox
Michelle Methot
Adrian Baranchuk
author_sort Michael Gysel
collection DOAJ
description A 71-year-old woman collapsed while working as a grocery store cashier. CPR was performed and an AED revealed torsades de pointes (TdP). She was subsequently defibrillated resulting in restoration of sinus rhythm with a QTc interval of 544 msec. Further evaluation revealed a diagnosis of Takotsubo Cardiomyopathy (TCM) contributing to the development of a multifactorial acquired long QT syndrome (LQTS). The case highlights the role of TCM as a cause of LQTS in the setting of multiple risk factors including old age, female gender, hypokalemia, and treatment with QT prolonging medications. It also highlights the multifactorial nature of acquired LQTS and lends support to growing evidence of an association with TCM.
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spelling doaj-art-17f1ed70f7d84231ac5398e517b31db12025-02-03T01:23:51ZengWileyCase Reports in Cardiology2090-64042090-64122014-01-01201410.1155/2014/213842213842Multifactorial QT Interval Prolongation and Takotsubo CardiomyopathyMichael Gysel0Alexander Crystal1Jules C. Hancox2Michelle Methot3Adrian Baranchuk4Department of Medicine, Kingston General Hospital, Queen’s University, Kingston, ON, K7L 3N6, CanadaDepartment of Medicine, Yale University, Bridgeport Hospital, Bridgeport, CT 06610, USASchool of Physiology and Pharmacology, University of Bristol, Bristol BS8 1TD, UKDepartment of Medicine, Kingston General Hospital, Queen’s University, Kingston, ON, K7L 3N6, CanadaDepartment of Medicine, Kingston General Hospital, Queen’s University, Kingston, ON, K7L 3N6, CanadaA 71-year-old woman collapsed while working as a grocery store cashier. CPR was performed and an AED revealed torsades de pointes (TdP). She was subsequently defibrillated resulting in restoration of sinus rhythm with a QTc interval of 544 msec. Further evaluation revealed a diagnosis of Takotsubo Cardiomyopathy (TCM) contributing to the development of a multifactorial acquired long QT syndrome (LQTS). The case highlights the role of TCM as a cause of LQTS in the setting of multiple risk factors including old age, female gender, hypokalemia, and treatment with QT prolonging medications. It also highlights the multifactorial nature of acquired LQTS and lends support to growing evidence of an association with TCM.http://dx.doi.org/10.1155/2014/213842
spellingShingle Michael Gysel
Alexander Crystal
Jules C. Hancox
Michelle Methot
Adrian Baranchuk
Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy
Case Reports in Cardiology
title Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy
title_full Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy
title_fullStr Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy
title_full_unstemmed Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy
title_short Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy
title_sort multifactorial qt interval prolongation and takotsubo cardiomyopathy
url http://dx.doi.org/10.1155/2014/213842
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