Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol
Introduction Neck pain (NP) is a common musculoskeletal complaint and is increasing in prevalence. Current clinical practice guidelines and systematic reviews recommended conservative, pharmacological and invasive interventions for individuals with NP. However, optimal management specifically for th...
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| Format: | Article |
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BMJ Publishing Group
2022-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/6/e060373.full |
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| author | Alison B Rushton Nicola R Heneghan Taweewat Wiangkham Uchukarn Boonyapo Piyameth Dilokthornsakul Nattawan Phungwattanakul |
| author_facet | Alison B Rushton Nicola R Heneghan Taweewat Wiangkham Uchukarn Boonyapo Piyameth Dilokthornsakul Nattawan Phungwattanakul |
| author_sort | Alison B Rushton |
| collection | DOAJ |
| description | Introduction Neck pain (NP) is a common musculoskeletal complaint and is increasing in prevalence. Current clinical practice guidelines and systematic reviews recommended conservative, pharmacological and invasive interventions for individuals with NP. However, optimal management specifically for those who are middle-aged or older adults (≥45 years) is not available; and important considering our ageing population.Methods and analysis A systematic review with network meta-analysis (NMA) will be conducted following the Cochrane guidelines. Eligibility criteria include randomised controlled/clinical trials evaluating any of acute (<3 months) or chronic (≥3 months) non-specific NP, whiplash associated disorders, cervical radiculopathy and cervicogenic headache. Any interventions and outcome measures detailed within The International Classification of Functioning, Disability and Health domains will be included. Two independent reviewers will search key databases (AMED, CENTRAL, CINAHL, Embase, MEDLINE, PEDro and PsycINFO), grey literature, key journals and reference lists in May 2022. Two reviewers will decide eligibility and assess risk of bias (ROB) of included studies. The kappa statistic will be used to evaluate agreement between the reviewers at each stage. Data will be extracted by one reviewer and checked for accuracy by a second reviewer. Descriptive data and ROB will be summarised and tabulated. Traditional pairwise meta-analysis using random-effect model will be performed for all direct comparisons, and NMA using a frequentist random-effect model then performed based on NP classification where possible. A network of traditional pairwise meta-analysis allows comparisons of multiple interventions from both direct and indirect evidence to provide a hierarchal establishment for enhancing decision making of clinical practitioners.Ethics and dissemination Ethic approval is not required as the study is a literature review. The findings will be shared with the national and international researchers, healthcare professionals and the general public through publishing in a peer-reviewed journal and presentations at conferences.PROSPERO registration number CRD42021284618. |
| format | Article |
| id | doaj-art-17f14445380f472dbbcf6641d4effab3 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-17f14445380f472dbbcf6641d4effab32025-01-28T05:30:09ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-060373Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocolAlison B Rushton0Nicola R Heneghan1Taweewat Wiangkham2Uchukarn Boonyapo3Piyameth Dilokthornsakul4Nattawan Phungwattanakul5School of Physical Therapy, Western University Faculty of Health Sciences, London, Ontario, CanadaCentre of Precision Rehabilitation for Spinal Pain (CPR Spine), School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK2 Department of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, ThailandDepartment of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, ThailandCenter of Pharmaceutical Outcomes Research (CPOR), Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, ThailandDepartment of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, ThailandIntroduction Neck pain (NP) is a common musculoskeletal complaint and is increasing in prevalence. Current clinical practice guidelines and systematic reviews recommended conservative, pharmacological and invasive interventions for individuals with NP. However, optimal management specifically for those who are middle-aged or older adults (≥45 years) is not available; and important considering our ageing population.Methods and analysis A systematic review with network meta-analysis (NMA) will be conducted following the Cochrane guidelines. Eligibility criteria include randomised controlled/clinical trials evaluating any of acute (<3 months) or chronic (≥3 months) non-specific NP, whiplash associated disorders, cervical radiculopathy and cervicogenic headache. Any interventions and outcome measures detailed within The International Classification of Functioning, Disability and Health domains will be included. Two independent reviewers will search key databases (AMED, CENTRAL, CINAHL, Embase, MEDLINE, PEDro and PsycINFO), grey literature, key journals and reference lists in May 2022. Two reviewers will decide eligibility and assess risk of bias (ROB) of included studies. The kappa statistic will be used to evaluate agreement between the reviewers at each stage. Data will be extracted by one reviewer and checked for accuracy by a second reviewer. Descriptive data and ROB will be summarised and tabulated. Traditional pairwise meta-analysis using random-effect model will be performed for all direct comparisons, and NMA using a frequentist random-effect model then performed based on NP classification where possible. A network of traditional pairwise meta-analysis allows comparisons of multiple interventions from both direct and indirect evidence to provide a hierarchal establishment for enhancing decision making of clinical practitioners.Ethics and dissemination Ethic approval is not required as the study is a literature review. The findings will be shared with the national and international researchers, healthcare professionals and the general public through publishing in a peer-reviewed journal and presentations at conferences.PROSPERO registration number CRD42021284618.https://bmjopen.bmj.com/content/12/6/e060373.full |
| spellingShingle | Alison B Rushton Nicola R Heneghan Taweewat Wiangkham Uchukarn Boonyapo Piyameth Dilokthornsakul Nattawan Phungwattanakul Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol BMJ Open |
| title | Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol |
| title_full | Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol |
| title_fullStr | Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol |
| title_full_unstemmed | Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol |
| title_short | Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol |
| title_sort | effectiveness of interventions for middle aged and ageing population with neck pain a systematic review and network meta analysis protocol |
| url | https://bmjopen.bmj.com/content/12/6/e060373.full |
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