Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience

Background. SARS-CoV-2 is a newly emerged virus that has spread rapidly, exhibiting tremendous morbidity and mortality. Some potential pharmaceutical targets have been identified but are still lacking proper validation. Case Presentation. We describe the case of a young, immunosuppressed and critica...

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Main Authors: Alejandro Sanchez-Nadales, Miguel Treminio-Quezada, Hasan Abad, Jessica Navarro-Motta, Pamela Contreras-Chavez, Anil Kachru, Chae Chu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2020/8877641
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author Alejandro Sanchez-Nadales
Miguel Treminio-Quezada
Hasan Abad
Jessica Navarro-Motta
Pamela Contreras-Chavez
Anil Kachru
Chae Chu
author_facet Alejandro Sanchez-Nadales
Miguel Treminio-Quezada
Hasan Abad
Jessica Navarro-Motta
Pamela Contreras-Chavez
Anil Kachru
Chae Chu
author_sort Alejandro Sanchez-Nadales
collection DOAJ
description Background. SARS-CoV-2 is a newly emerged virus that has spread rapidly, exhibiting tremendous morbidity and mortality. Some potential pharmaceutical targets have been identified but are still lacking proper validation. Case Presentation. We describe the case of a young, immunosuppressed and critically ill patient with previous Influenza B infection, requiring extracorporeal membrane oxygenation, which was then followed, in the succeeding months, by SARS-CoV-2 infection complicated by severe adult respiratory distress syndrome. Her clinical course exhibited complications, including pulmonary embolism, acute kidney injury, pneumothorax, pneumomediastinum, multiple cardiac arrests, and eventually death. Conclusion. Coinfection with other respiratory pathogens and opportunistic infections are possible.
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institution Kabale University
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publisher Wiley
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spelling doaj-art-17e83dd4fb3043d0ae56b2b08c0028482025-02-03T01:24:56ZengWileyCase Reports in Critical Care2090-64202090-64392020-01-01202010.1155/2020/88776418877641Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago ExperienceAlejandro Sanchez-Nadales0Miguel Treminio-Quezada1Hasan Abad2Jessica Navarro-Motta3Pamela Contreras-Chavez4Anil Kachru5Chae Chu6Department of Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Pulmonology and Critical Care Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USADepartment of Pulmonology and Critical Care Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, USABackground. SARS-CoV-2 is a newly emerged virus that has spread rapidly, exhibiting tremendous morbidity and mortality. Some potential pharmaceutical targets have been identified but are still lacking proper validation. Case Presentation. We describe the case of a young, immunosuppressed and critically ill patient with previous Influenza B infection, requiring extracorporeal membrane oxygenation, which was then followed, in the succeeding months, by SARS-CoV-2 infection complicated by severe adult respiratory distress syndrome. Her clinical course exhibited complications, including pulmonary embolism, acute kidney injury, pneumothorax, pneumomediastinum, multiple cardiac arrests, and eventually death. Conclusion. Coinfection with other respiratory pathogens and opportunistic infections are possible.http://dx.doi.org/10.1155/2020/8877641
spellingShingle Alejandro Sanchez-Nadales
Miguel Treminio-Quezada
Hasan Abad
Jessica Navarro-Motta
Pamela Contreras-Chavez
Anil Kachru
Chae Chu
Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience
Case Reports in Critical Care
title Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience
title_full Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience
title_fullStr Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience
title_full_unstemmed Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience
title_short Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience
title_sort critical care management for novel 2019 sars cov 2 and hcov nl63 coinfection in a young immunocompromised patient a chicago experience
url http://dx.doi.org/10.1155/2020/8877641
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