Regulation of S100A8/A9 (Calprotectin) Binding to Tumor Cells by Zinc Ion and Its Implication for Apoptosis-Inducing Activity

S100A8/A9 (calprotectin), which is released by neutrophils under inflammatory conditions, has the capacity to induce apoptosis in various cells. We previously reported that S100A8/A9 induces apoptosis of EL-4 lymphoma cells via the uptake of extracellular zinc in a manner similar to DTPA, a membrane...

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Bibliographic Details
Main Authors: Yuichi Nakatani, Masatoshi Yamazaki, Walter J. Chazin, Satoru Yui
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/MI.2005.280
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