Regulation of S100A8/A9 (Calprotectin) Binding to Tumor Cells by Zinc Ion and Its Implication for Apoptosis-Inducing Activity
S100A8/A9 (calprotectin), which is released by neutrophils under inflammatory conditions, has the capacity to induce apoptosis in various cells. We previously reported that S100A8/A9 induces apoptosis of EL-4 lymphoma cells via the uptake of extracellular zinc in a manner similar to DTPA, a membrane...
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Main Authors: | Yuichi Nakatani, Masatoshi Yamazaki, Walter J. Chazin, Satoru Yui |
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Format: | Article |
Language: | English |
Published: |
Wiley
2005-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/MI.2005.280 |
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