Extra-ocular sebaceous carcinoma - A rare case report
Sebaceous gland carcinoma is a rare and aggressive skin cancer derived from the sebaceous glands. Sebaceous carcinomas are divided into those occurring in ocular (75%) and extra-ocular locations. A 45-year-old female patient presented with rapidly growing swelling over the upper back region. It was...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_860_21 |
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| author | Manda Sindhura Tummidi Santosh Jarang Rajesh Kumar Arundhathi Shankaralingappa Naresh Kumar Pannerselvam Pavithra Balakrishna |
| author_facet | Manda Sindhura Tummidi Santosh Jarang Rajesh Kumar Arundhathi Shankaralingappa Naresh Kumar Pannerselvam Pavithra Balakrishna |
| author_sort | Manda Sindhura |
| collection | DOAJ |
| description | Sebaceous gland carcinoma is a rare and aggressive skin cancer derived from the sebaceous glands. Sebaceous carcinomas are divided into those occurring in ocular (75%) and extra-ocular locations. A 45-year-old female patient presented with rapidly growing swelling over the upper back region. It was provisionally diagnosed as an infected sebaceous cyst, and an excision biopsy was received in the pathology department. Histopathology was reported as sebaceous carcinoma, Grade II, Stage P T3 Nx. Immunohistochemistry was positive for epithelial membrane antigen. Sebaceous carcinoma accounts for 0.2–4.6% of all malignant cutaneous neoplasms, and the estimated rate of occurrence is only 1–2 per 1 million individuals per year. These tumors frequently present with a painless sub-cutaneous nodule, but they can also present as pedunculated lesions, irregular mass, or diffuse thickening of the skin. Hence, they are misinterpreted as other benign tumors or inflammatory conditions, thereby leading to delay in diagnosis, inappropriate treatment, increased morbidity, and mortality. |
| format | Article |
| id | doaj-art-1787b9d30c2e4e62bdb4d55425075f25 |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-1787b9d30c2e4e62bdb4d55425075f252025-01-22T15:13:28ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302023-01-0167116917110.4103/ijpm.ijpm_860_21Extra-ocular sebaceous carcinoma - A rare case reportManda SindhuraTummidi SantoshJarang Rajesh KumarArundhathi ShankaralingappaNaresh Kumar PannerselvamPavithra BalakrishnaSebaceous gland carcinoma is a rare and aggressive skin cancer derived from the sebaceous glands. Sebaceous carcinomas are divided into those occurring in ocular (75%) and extra-ocular locations. A 45-year-old female patient presented with rapidly growing swelling over the upper back region. It was provisionally diagnosed as an infected sebaceous cyst, and an excision biopsy was received in the pathology department. Histopathology was reported as sebaceous carcinoma, Grade II, Stage P T3 Nx. Immunohistochemistry was positive for epithelial membrane antigen. Sebaceous carcinoma accounts for 0.2–4.6% of all malignant cutaneous neoplasms, and the estimated rate of occurrence is only 1–2 per 1 million individuals per year. These tumors frequently present with a painless sub-cutaneous nodule, but they can also present as pedunculated lesions, irregular mass, or diffuse thickening of the skin. Hence, they are misinterpreted as other benign tumors or inflammatory conditions, thereby leading to delay in diagnosis, inappropriate treatment, increased morbidity, and mortality.https://journals.lww.com/10.4103/ijpm.ijpm_860_21emaextra-ocularimmunohistochemistryrecurrencesebaceous carcinoma |
| spellingShingle | Manda Sindhura Tummidi Santosh Jarang Rajesh Kumar Arundhathi Shankaralingappa Naresh Kumar Pannerselvam Pavithra Balakrishna Extra-ocular sebaceous carcinoma - A rare case report Indian Journal of Pathology and Microbiology ema extra-ocular immunohistochemistry recurrence sebaceous carcinoma |
| title | Extra-ocular sebaceous carcinoma - A rare case report |
| title_full | Extra-ocular sebaceous carcinoma - A rare case report |
| title_fullStr | Extra-ocular sebaceous carcinoma - A rare case report |
| title_full_unstemmed | Extra-ocular sebaceous carcinoma - A rare case report |
| title_short | Extra-ocular sebaceous carcinoma - A rare case report |
| title_sort | extra ocular sebaceous carcinoma a rare case report |
| topic | ema extra-ocular immunohistochemistry recurrence sebaceous carcinoma |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_860_21 |
| work_keys_str_mv | AT mandasindhura extraocularsebaceouscarcinomaararecasereport AT tummidisantosh extraocularsebaceouscarcinomaararecasereport AT jarangrajeshkumar extraocularsebaceouscarcinomaararecasereport AT arundhathishankaralingappa extraocularsebaceouscarcinomaararecasereport AT nareshkumarpannerselvam extraocularsebaceouscarcinomaararecasereport AT pavithrabalakrishna extraocularsebaceouscarcinomaararecasereport |