Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain
Since its discovery in 1994, Kaposi's sarcoma-associated herpesvirus (KSHV) has been associated with lymphoproliferative disorders, particularly in patients infected with human immunodeficiency virus...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | AIDS Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2011/729854 |
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| _version_ | 1832548523719000064 |
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| author | Jason R. Andrews Yoon Andrew Cho-Park Judith Ferry Jeremy S. Abramson Gregory K. Robbins |
| author_facet | Jason R. Andrews Yoon Andrew Cho-Park Judith Ferry Jeremy S. Abramson Gregory K. Robbins |
| author_sort | Jason R. Andrews |
| collection | DOAJ |
| description | Since its discovery
in 1994, Kaposi's sarcoma-associated
herpesvirus (KSHV) has been associated with
lymphoproliferative disorders, particularly in
patients infected with human immunodeficiency
virus (HIV). The disorders most strongly linked
to KSHV are multicentric Castleman's Disease
(MCD), primary effusion lymphoma, and diffuse
large B-cell lymphomas. We report an unusual
case of KSHV-associated lymphoma in an
HIV-infected patient manifesting with myocardial
and central nervous system involvement. We
discuss this case in the context of increasing
array of KSHV-associated lymphomas. In the
HIV-infected patient with a mass lesion, a
history of cutaneous Kaposi's sarcoma and
prolonged immunosuppression should alert
clinicians as to the possibility of
KSHV-associated lymphoproliferative disorders,
in order to establish a timely
diagnosis. |
| format | Article |
| id | doaj-art-177d81c31b814976a7ede12c1ca7da35 |
| institution | Kabale University |
| issn | 2090-1240 2090-1259 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | AIDS Research and Treatment |
| spelling | doaj-art-177d81c31b814976a7ede12c1ca7da352025-02-03T06:13:41ZengWileyAIDS Research and Treatment2090-12402090-12592011-01-01201110.1155/2011/729854729854Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and BrainJason R. Andrews0Yoon Andrew Cho-Park1Judith Ferry2Jeremy S. Abramson3Gregory K. Robbins4Division of Infectious Diseases, Massachusetts General Hospital, 55 Fruit Street, Cox 506, Boston, MA 02114, USAHarvard Medical School, Boston, MA 02115, USAHarvard Medical School, Boston, MA 02115, USAHarvard Medical School, Boston, MA 02115, USADivision of Infectious Diseases, Massachusetts General Hospital, 55 Fruit Street, Cox 506, Boston, MA 02114, USASince its discovery in 1994, Kaposi's sarcoma-associated herpesvirus (KSHV) has been associated with lymphoproliferative disorders, particularly in patients infected with human immunodeficiency virus (HIV). The disorders most strongly linked to KSHV are multicentric Castleman's Disease (MCD), primary effusion lymphoma, and diffuse large B-cell lymphomas. We report an unusual case of KSHV-associated lymphoma in an HIV-infected patient manifesting with myocardial and central nervous system involvement. We discuss this case in the context of increasing array of KSHV-associated lymphomas. In the HIV-infected patient with a mass lesion, a history of cutaneous Kaposi's sarcoma and prolonged immunosuppression should alert clinicians as to the possibility of KSHV-associated lymphoproliferative disorders, in order to establish a timely diagnosis.http://dx.doi.org/10.1155/2011/729854 |
| spellingShingle | Jason R. Andrews Yoon Andrew Cho-Park Judith Ferry Jeremy S. Abramson Gregory K. Robbins Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain AIDS Research and Treatment |
| title | Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain |
| title_full | Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain |
| title_fullStr | Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain |
| title_full_unstemmed | Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain |
| title_short | Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain |
| title_sort | kaposi s sarcoma associated herpesvirus related solid lymphoma involving the heart and brain |
| url | http://dx.doi.org/10.1155/2011/729854 |
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