A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in Turkey

Purpose. To report a case of medication-resistant acanthamoeba keratitis (AK) treated successfully by corneal crosslinking (CXL). Methods. A 26-year-old male with medication-resistant AK underwent a standard CXL procedure with local anesthesia, followed by central corneal epithelial debridement, app...

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Main Authors: Goktug Demirci, Akif Ozdamar
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2013/608253
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author Goktug Demirci
Akif Ozdamar
author_facet Goktug Demirci
Akif Ozdamar
author_sort Goktug Demirci
collection DOAJ
description Purpose. To report a case of medication-resistant acanthamoeba keratitis (AK) treated successfully by corneal crosslinking (CXL). Methods. A 26-year-old male with medication-resistant AK underwent a standard CXL procedure with local anesthesia, followed by central corneal epithelial debridement, application of riboflavin 0.1%, and UV-A irradiation. Results. The patient experienced a dramatic symptomatic improvement within 24 hours. At two months, keratitis was healed with a semitransparent paracentral scar that did not affect visual acuity. Conclusions. Our experience, considered in the context of recent studies, suggests that CXL may be an option for selected patients with medication-resistant AK and corneal melting. CXL allows patients to avoid emergency keratoplasty and experience rapid symptomatic relief.
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spelling doaj-art-17783323a42d43b181daa96fddc9f2b22025-02-03T01:12:01ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302013-01-01201310.1155/2013/608253608253A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in TurkeyGoktug Demirci0Akif Ozdamar1Department of Ophthalmology, Medipol University Hospital, 34800 Istanbul, TurkeyDepartment of Ophthalmology, Cerrahpasa Medical Faculty of Istanbul University, 34800 Istanbul, TurkeyPurpose. To report a case of medication-resistant acanthamoeba keratitis (AK) treated successfully by corneal crosslinking (CXL). Methods. A 26-year-old male with medication-resistant AK underwent a standard CXL procedure with local anesthesia, followed by central corneal epithelial debridement, application of riboflavin 0.1%, and UV-A irradiation. Results. The patient experienced a dramatic symptomatic improvement within 24 hours. At two months, keratitis was healed with a semitransparent paracentral scar that did not affect visual acuity. Conclusions. Our experience, considered in the context of recent studies, suggests that CXL may be an option for selected patients with medication-resistant AK and corneal melting. CXL allows patients to avoid emergency keratoplasty and experience rapid symptomatic relief.http://dx.doi.org/10.1155/2013/608253
spellingShingle Goktug Demirci
Akif Ozdamar
A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in Turkey
Case Reports in Ophthalmological Medicine
title A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in Turkey
title_full A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in Turkey
title_fullStr A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in Turkey
title_full_unstemmed A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in Turkey
title_short A Case of Medication-Resistant Acanthamoeba Keratitis Treated by Corneal Crosslinking in Turkey
title_sort case of medication resistant acanthamoeba keratitis treated by corneal crosslinking in turkey
url http://dx.doi.org/10.1155/2013/608253
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