The Importance of Radiological Patterns and Small Airway Disease in Long-Term Follow-Up of Postacute COVID-19: A Preliminary Study
Postacute COVID-19 has become a relevant public health problem, and radiological and pulmonary function tests are tools that help physicians in decision-making. The objectives of this study are to characterize the findings and patterns on a chest radiograph (CXR) and computed tomography (CT) that ar...
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Wiley
2022-01-01
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| Series: | Radiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2022/7919033 |
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| author | Roberto Mogami Ronaldo Carvalho Araújo Filho Carolina Gianella Cobo Chantong Fernando Carlos Santos de Almeida Ana Célia Baptista Koifman Gustavo Federico Jauregui Thiago Thomaz Mafort Hanna da Silva Bessa da Costa Glenda Aparecida Peres dos Santos Bruna Zangerolame de Carvalho Gabriel da Silva Passos Erick de Souza Barbosa Angelo Thomaz Abalada Ghetti Laura Braga Monnerat Mariana Soares da Cal Desiree Louise Souza Santos Batista Helen Aksenow Affonso Gabriel Oliveira Bousquet Jose Ignacio Marenco Avila Anna Luiza Bento Dutra Caio Leal Leidersnaider Alexandre Malta da Costa Messeder Alexandra Monteiro Agnaldo José Lopes |
| author_facet | Roberto Mogami Ronaldo Carvalho Araújo Filho Carolina Gianella Cobo Chantong Fernando Carlos Santos de Almeida Ana Célia Baptista Koifman Gustavo Federico Jauregui Thiago Thomaz Mafort Hanna da Silva Bessa da Costa Glenda Aparecida Peres dos Santos Bruna Zangerolame de Carvalho Gabriel da Silva Passos Erick de Souza Barbosa Angelo Thomaz Abalada Ghetti Laura Braga Monnerat Mariana Soares da Cal Desiree Louise Souza Santos Batista Helen Aksenow Affonso Gabriel Oliveira Bousquet Jose Ignacio Marenco Avila Anna Luiza Bento Dutra Caio Leal Leidersnaider Alexandre Malta da Costa Messeder Alexandra Monteiro Agnaldo José Lopes |
| author_sort | Roberto Mogami |
| collection | DOAJ |
| description | Postacute COVID-19 has become a relevant public health problem, and radiological and pulmonary function tests are tools that help physicians in decision-making. The objectives of this study are to characterize the findings and patterns on a chest radiograph (CXR) and computed tomography (CT) that are most important in the postacute phase and to evaluate how these changes correlate with clinical data, spirometry, and impulse oscillometry (IOS). This was a retrospective study of 29 patients who underwent CXR, CT, spirometry, and IOS. The inclusion criteria were age >18 years and persistent respiratory symptoms after four weeks. The exclusion criteria were radiological exams with low technical quality and non-COVID-19 acute lung diseases. The inferential analysis was carried out with the chi-square (χ2) or Fisher’s exact test to evaluate the interrelationships between the clinical and COVID-19 variables according to spirometry, IOS, CT, and CXR. In our sample, 19 patients were women (65.5%). The predominance of abnormal spirometry was associated with CT’s moderate/severe degree of involvement (p = 0.017; 69.2%, CI 95%: 44.1%–94.3%). There was no significant association between IOS and tomographic and radiographic parameters. A significant association was found between the classifications of the moderate/severe and normal/mild patterns on CT and CXRs (p = 0.003; 93.3%, CI 95%: 77.8%–100%). Patients with moderate/severe impairment on CXR were associated with a higher frequency of hospitalization (p = 0.033; 77.8%, CI 95%: 58.6%–97.0%) and had significantly more moderate/severe classifications in the acute phase than the subgroup with normal/mild impairment on CXR (p = 0.017; 88.9%, CI 95%: 74.4%–100%). In conclusion, the results of this study show that CXR is a relevant examination and may be used to detect nonspecific alterations during the follow-up of post-COVID-19 patients. Small airway disease is an important finding in postacute COVID-19 syndrome, and we postulate a connection between this pattern and the persistently low-level inflammatory state of the lung. |
| format | Article |
| id | doaj-art-1754e7272f7b407d9ed11068f9e1584d |
| institution | Kabale University |
| issn | 2090-195X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Radiology Research and Practice |
| spelling | doaj-art-1754e7272f7b407d9ed11068f9e1584d2025-02-03T05:53:50ZengWileyRadiology Research and Practice2090-195X2022-01-01202210.1155/2022/7919033The Importance of Radiological Patterns and Small Airway Disease in Long-Term Follow-Up of Postacute COVID-19: A Preliminary StudyRoberto Mogami0Ronaldo Carvalho Araújo Filho1Carolina Gianella Cobo Chantong2Fernando Carlos Santos de Almeida3Ana Célia Baptista Koifman4Gustavo Federico Jauregui5Thiago Thomaz Mafort6Hanna da Silva Bessa da Costa7Glenda Aparecida Peres dos Santos8Bruna Zangerolame de Carvalho9Gabriel da Silva Passos10Erick de Souza Barbosa11Angelo Thomaz Abalada Ghetti12Laura Braga Monnerat13Mariana Soares da Cal14Desiree Louise Souza Santos Batista15Helen Aksenow Affonso16Gabriel Oliveira Bousquet17Jose Ignacio Marenco Avila18Anna Luiza Bento Dutra19Caio Leal Leidersnaider20Alexandre Malta da Costa Messeder21Alexandra Monteiro22Agnaldo José Lopes23Department of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of PulmonologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of PulmonologyDepartment of PulmonologyDepartment of PulmonologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyMedical Sciences Post-Graduation ProgramPostacute COVID-19 has become a relevant public health problem, and radiological and pulmonary function tests are tools that help physicians in decision-making. The objectives of this study are to characterize the findings and patterns on a chest radiograph (CXR) and computed tomography (CT) that are most important in the postacute phase and to evaluate how these changes correlate with clinical data, spirometry, and impulse oscillometry (IOS). This was a retrospective study of 29 patients who underwent CXR, CT, spirometry, and IOS. The inclusion criteria were age >18 years and persistent respiratory symptoms after four weeks. The exclusion criteria were radiological exams with low technical quality and non-COVID-19 acute lung diseases. The inferential analysis was carried out with the chi-square (χ2) or Fisher’s exact test to evaluate the interrelationships between the clinical and COVID-19 variables according to spirometry, IOS, CT, and CXR. In our sample, 19 patients were women (65.5%). The predominance of abnormal spirometry was associated with CT’s moderate/severe degree of involvement (p = 0.017; 69.2%, CI 95%: 44.1%–94.3%). There was no significant association between IOS and tomographic and radiographic parameters. A significant association was found between the classifications of the moderate/severe and normal/mild patterns on CT and CXRs (p = 0.003; 93.3%, CI 95%: 77.8%–100%). Patients with moderate/severe impairment on CXR were associated with a higher frequency of hospitalization (p = 0.033; 77.8%, CI 95%: 58.6%–97.0%) and had significantly more moderate/severe classifications in the acute phase than the subgroup with normal/mild impairment on CXR (p = 0.017; 88.9%, CI 95%: 74.4%–100%). In conclusion, the results of this study show that CXR is a relevant examination and may be used to detect nonspecific alterations during the follow-up of post-COVID-19 patients. Small airway disease is an important finding in postacute COVID-19 syndrome, and we postulate a connection between this pattern and the persistently low-level inflammatory state of the lung.http://dx.doi.org/10.1155/2022/7919033 |
| spellingShingle | Roberto Mogami Ronaldo Carvalho Araújo Filho Carolina Gianella Cobo Chantong Fernando Carlos Santos de Almeida Ana Célia Baptista Koifman Gustavo Federico Jauregui Thiago Thomaz Mafort Hanna da Silva Bessa da Costa Glenda Aparecida Peres dos Santos Bruna Zangerolame de Carvalho Gabriel da Silva Passos Erick de Souza Barbosa Angelo Thomaz Abalada Ghetti Laura Braga Monnerat Mariana Soares da Cal Desiree Louise Souza Santos Batista Helen Aksenow Affonso Gabriel Oliveira Bousquet Jose Ignacio Marenco Avila Anna Luiza Bento Dutra Caio Leal Leidersnaider Alexandre Malta da Costa Messeder Alexandra Monteiro Agnaldo José Lopes The Importance of Radiological Patterns and Small Airway Disease in Long-Term Follow-Up of Postacute COVID-19: A Preliminary Study Radiology Research and Practice |
| title | The Importance of Radiological Patterns and Small Airway Disease in Long-Term Follow-Up of Postacute COVID-19: A Preliminary Study |
| title_full | The Importance of Radiological Patterns and Small Airway Disease in Long-Term Follow-Up of Postacute COVID-19: A Preliminary Study |
| title_fullStr | The Importance of Radiological Patterns and Small Airway Disease in Long-Term Follow-Up of Postacute COVID-19: A Preliminary Study |
| title_full_unstemmed | The Importance of Radiological Patterns and Small Airway Disease in Long-Term Follow-Up of Postacute COVID-19: A Preliminary Study |
| title_short | The Importance of Radiological Patterns and Small Airway Disease in Long-Term Follow-Up of Postacute COVID-19: A Preliminary Study |
| title_sort | importance of radiological patterns and small airway disease in long term follow up of postacute covid 19 a preliminary study |
| url | http://dx.doi.org/10.1155/2022/7919033 |
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