Embryologic Association of Tornwaldt's Cyst with Cerebral Artery Abnormalities and Infarction: A Case Report

Background and Purpose. Tornwaldt's cysts are rare nasopharyngeal lesions that develop from remnants of the embryonic notochord. Summary of Case. We reported a twelve-year-old female stroke patient with Tornwaldt's cysts, whose father also suffered a stroke at age fifty two with the presen...

Full description

Saved in:
Bibliographic Details
Main Authors: Michael F. Osborn, Benjamin K. Buchanan, Nassim Akle, Ahmed Badr, Jun Zhang
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2012/129503
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background and Purpose. Tornwaldt's cysts are rare nasopharyngeal lesions that develop from remnants of the embryonic notochord. Summary of Case. We reported a twelve-year-old female stroke patient with Tornwaldt's cysts, whose father also suffered a stroke at age fifty two with the presence of an abdominal aortic aneurysm, suggesting a genetic influence in this case. Conclusions. This paper suggests an etiologic connection between Tornwaldt's cysts and cerebral vasculature abnormalities by way of notochordal dysfunction during development, likely the result of perturbation of notochord-derived molecular cues during development or biogenesis.
ISSN:2090-6803
2090-6811