in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes
In this study, Antioxidant activity of Cyperus rotundus rhizomes extract (CRRE) was evaluveted in a series of in vitro assay involving free radicals and reactive oxygen species and IC50 values were determined. CRRE exhibited its scavenging effect in concentration dependent manner on superoxide anion...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2007/903496 |
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| author | KR. Nagulendran S. Velavan R. Mahesh V. Hazeena Begum |
| author_facet | KR. Nagulendran S. Velavan R. Mahesh V. Hazeena Begum |
| author_sort | KR. Nagulendran |
| collection | DOAJ |
| description | In this study, Antioxidant activity of Cyperus rotundus rhizomes extract (CRRE) was evaluveted in a series of in vitro assay involving free radicals and reactive oxygen species and IC50 values were determined. CRRE exhibited its scavenging effect in concentration dependent manner on superoxide anion radicals, hydroxyl radicals, nitric oxide radical, hydrogen peroxide, and property of metal chelating and reducing power. The extract was also studied for lipid peroxidation assay by thiobarbituric acid–reactive substances (TBARS) using young and aged rat brain mitochondria. The extract was also effective in preventing mitochondrial lipid peroxidation induced by FeSO4/ ascorbate in concentration dependent manner. The results obtained in the present study indicate that C. rotundus rhizomes extract can be a potential source of natural antioxidant. |
| format | Article |
| id | doaj-art-1747618dd70b45f180f628a5dda2e12a |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-1747618dd70b45f180f628a5dda2e12a2025-02-03T01:07:14ZengWileyE-Journal of Chemistry0973-49452090-98102007-01-014344044910.1155/2007/903496in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus RhizomesKR. Nagulendran0S. Velavan1R. Mahesh2V. Hazeena Begum3Department of Siddha Medicine, Faculty of Science, Tamil University, Vakaiyur, Thanjavur-613 005, Tamilnadu, IndiaDepartment of Siddha Medicine, Faculty of Science, Tamil University, Vakaiyur, Thanjavur-613 005, Tamilnadu, IndiaDepartment of Siddha Medicine, Faculty of Science, Tamil University, Vakaiyur, Thanjavur-613 005, Tamilnadu, IndiaDepartment of Siddha Medicine, Faculty of Science, Tamil University, Vakaiyur, Thanjavur-613 005, Tamilnadu, IndiaIn this study, Antioxidant activity of Cyperus rotundus rhizomes extract (CRRE) was evaluveted in a series of in vitro assay involving free radicals and reactive oxygen species and IC50 values were determined. CRRE exhibited its scavenging effect in concentration dependent manner on superoxide anion radicals, hydroxyl radicals, nitric oxide radical, hydrogen peroxide, and property of metal chelating and reducing power. The extract was also studied for lipid peroxidation assay by thiobarbituric acid–reactive substances (TBARS) using young and aged rat brain mitochondria. The extract was also effective in preventing mitochondrial lipid peroxidation induced by FeSO4/ ascorbate in concentration dependent manner. The results obtained in the present study indicate that C. rotundus rhizomes extract can be a potential source of natural antioxidant.http://dx.doi.org/10.1155/2007/903496 |
| spellingShingle | KR. Nagulendran S. Velavan R. Mahesh V. Hazeena Begum in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes E-Journal of Chemistry |
| title | in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes |
| title_full | in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes |
| title_fullStr | in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes |
| title_full_unstemmed | in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes |
| title_short | in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes |
| title_sort | in vitro antioxidant activity and total polyphenolic content of cyperus rotundus rhizomes |
| url | http://dx.doi.org/10.1155/2007/903496 |
| work_keys_str_mv | AT krnagulendran invitroantioxidantactivityandtotalpolyphenoliccontentofcyperusrotundusrhizomes AT svelavan invitroantioxidantactivityandtotalpolyphenoliccontentofcyperusrotundusrhizomes AT rmahesh invitroantioxidantactivityandtotalpolyphenoliccontentofcyperusrotundusrhizomes AT vhazeenabegum invitroantioxidantactivityandtotalpolyphenoliccontentofcyperusrotundusrhizomes |