A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocomposite
Background and purpose: Dopamine has an impact on the cardiovascular, endocrine, renal, and central neurological systems. Electrochemical techniques are becoming more and more popular among researchers as a way to assess dopamine and uric acid levels. Experimental approach: Using electrochemical te...
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| Format: | Article |
| Language: | English |
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International Association of Physical Chemists (IAPC)
2025-02-01
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| Series: | ADMET and DMPK |
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| Online Access: | https://pub.iapchem.org/ojs/index.php/admet/article/view/2593 |
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| author | Azhar Hameed Gatea Aseer Shakir Ajel Raed Muslim Muhibes |
| author_facet | Azhar Hameed Gatea Aseer Shakir Ajel Raed Muslim Muhibes |
| author_sort | Azhar Hameed Gatea |
| collection | DOAJ |
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Background and purpose: Dopamine has an impact on the cardiovascular, endocrine, renal, and central neurological systems. Electrochemical techniques are becoming more and more popular among researchers as a way to assess dopamine and uric acid levels. Experimental approach: Using electrochemical techniques, a new Universitet i Oslo MOF (UiO-66)-graphene oxide nanocomposite-modified carbon paste electrode was created to investigate the electrooxidation of uric acid and dopamine as well as their combinations. At the redesigned electrode, uric acid and dopamine were detected concurrently in a very sensitive way using differential pulse voltammetry (DPV). Key results: Dopamine DPV peak currents increase in a linear fashion at doses between 0.05 and 600.0 µM. Conclusion: Uric acid and dopamine levels in urine and dopamine injection samples may be determined with the help of the proposed sensor, which is reasonably priced and performs well.
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| format | Article |
| id | doaj-art-172d99ed92c84caba90787198768c3ec |
| institution | Kabale University |
| issn | 1848-7718 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | International Association of Physical Chemists (IAPC) |
| record_format | Article |
| series | ADMET and DMPK |
| spelling | doaj-art-172d99ed92c84caba90787198768c3ec2025-02-05T07:56:07ZengInternational Association of Physical Chemists (IAPC)ADMET and DMPK1848-77182025-02-0110.5599/admet.2593A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocompositeAzhar Hameed Gatea 0Aseer Shakir Ajel 1Raed Muslim Muhibes2Department of Pathological Analytics Science, College of Applied Medical Science, Shatrah University, Thi-Qar, 64001 Iraq Department of Pathological Analytics Science, College of Applied Medical Science, Shatrah University, Thi-Qar, 64001, Iraq Department of Biochemistry, College of Medicine Misan University, Iraq Background and purpose: Dopamine has an impact on the cardiovascular, endocrine, renal, and central neurological systems. Electrochemical techniques are becoming more and more popular among researchers as a way to assess dopamine and uric acid levels. Experimental approach: Using electrochemical techniques, a new Universitet i Oslo MOF (UiO-66)-graphene oxide nanocomposite-modified carbon paste electrode was created to investigate the electrooxidation of uric acid and dopamine as well as their combinations. At the redesigned electrode, uric acid and dopamine were detected concurrently in a very sensitive way using differential pulse voltammetry (DPV). Key results: Dopamine DPV peak currents increase in a linear fashion at doses between 0.05 and 600.0 µM. Conclusion: Uric acid and dopamine levels in urine and dopamine injection samples may be determined with the help of the proposed sensor, which is reasonably priced and performs well. https://pub.iapchem.org/ojs/index.php/admet/article/view/2593Voltammetrychemically modified electrodesreal sample analysiselectrochemical sensor |
| spellingShingle | Azhar Hameed Gatea Aseer Shakir Ajel Raed Muslim Muhibes A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocomposite ADMET and DMPK Voltammetry chemically modified electrodes real sample analysis electrochemical sensor |
| title | A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocomposite |
| title_full | A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocomposite |
| title_fullStr | A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocomposite |
| title_full_unstemmed | A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocomposite |
| title_short | A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocomposite |
| title_sort | new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the uio 66 metal organic framework graphene oxide nanocomposite |
| topic | Voltammetry chemically modified electrodes real sample analysis electrochemical sensor |
| url | https://pub.iapchem.org/ojs/index.php/admet/article/view/2593 |
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