Comprehensive genomic analysis in sporadic early-onset colorectal adenocarcinoma patients

Comprehensive genomic analysis in sporadic early-onset colorectal adenocarcinoma patients

Abstract Background The incidence of colorectal cancer (CRC) in young adults has increased worldwide. Our study aimed to evaluate genomic alterations in early-onset (aged 15–39 years) sporadic CRC. Methods Formalin-fixed, paraffin-embedded tissue samples from 90 patients with histologically confirme...

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Bibliographic Details
Main Authors: Ben Ponvilawan, Phuwanat Sakornsakolpat, Ananya Pongpaibul, Ekkapong Roothumnong, Charuwan Akewanlop, Manop Pithukpakorn, Krittiya Korphaisarn
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
Genomic alterations
Molecular characteristic
Early onset
Adolescent and young adult
Colorectal cancer
Online Access:https://doi.org/10.1186/s12885-025-13745-5
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