Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B
After experimental inoculation of broiler chickens with subtype A avian metapneumovirus isolate, mild clinical signs were observed on days 6-14 after inoculation. The infected chickens demonstrated slight increase of T-helpers activity in blood, poor specific antibody response, development of specif...
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Da Vinci Media
2018-04-01
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Series: | Ветеринария сегодня |
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Online Access: | https://veterinary.arriah.ru/jour/article/view/282 |
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author | P. S. Yaroslavtseva M. A. Volkova Z. B. Nikonova N. S. Mudrak Ir. A. Chvala |
author_facet | P. S. Yaroslavtseva M. A. Volkova Z. B. Nikonova N. S. Mudrak Ir. A. Chvala |
author_sort | P. S. Yaroslavtseva |
collection | DOAJ |
description | After experimental inoculation of broiler chickens with subtype A avian metapneumovirus isolate, mild clinical signs were observed on days 6-14 after inoculation. The infected chickens demonstrated slight increase of T-helpers activity in blood, poor specific antibody response, development of specific secretory antibodies. Subtype B avian metapneumovirus isolate caused a somewhat more obvious specific clinical signs in chickens compared with subtype A on days 5-15 after inoculation, however, in both experiments, clinical signs completely disappeared in 14-15 days after infection. The increase of relative number of cytotoxic T lymphocytes in blood and in spleen, specific antibody response in 50-70% of chickens and activation of local immune response in 50% of chickens were observed in inoculated chickens. |
format | Article |
id | doaj-art-1726efbbcc674ce19fb36ad59bec5707 |
institution | Kabale University |
issn | 2304-196X 2658-6959 |
language | English |
publishDate | 2018-04-01 |
publisher | Da Vinci Media |
record_format | Article |
series | Ветеринария сегодня |
spelling | doaj-art-1726efbbcc674ce19fb36ad59bec57072025-02-06T09:52:06ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592018-04-01011722282Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and BP. S. Yaroslavtseva0M. A. Volkova1Z. B. Nikonova2N. S. Mudrak3Ir. A. Chvala4FGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirAfter experimental inoculation of broiler chickens with subtype A avian metapneumovirus isolate, mild clinical signs were observed on days 6-14 after inoculation. The infected chickens demonstrated slight increase of T-helpers activity in blood, poor specific antibody response, development of specific secretory antibodies. Subtype B avian metapneumovirus isolate caused a somewhat more obvious specific clinical signs in chickens compared with subtype A on days 5-15 after inoculation, however, in both experiments, clinical signs completely disappeared in 14-15 days after infection. The increase of relative number of cytotoxic T lymphocytes in blood and in spleen, specific antibody response in 50-70% of chickens and activation of local immune response in 50% of chickens were observed in inoculated chickens.https://veterinary.arriah.ru/jour/article/view/282метапневмовирус птициммунный ответэкспериментальное заражениеavian metapneumovirusimmune responseexperimental inoculation |
spellingShingle | P. S. Yaroslavtseva M. A. Volkova Z. B. Nikonova N. S. Mudrak Ir. A. Chvala Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B Ветеринария сегодня метапневмовирус птиц иммунный ответ экспериментальное заражение avian metapneumovirus immune response experimental inoculation |
title | Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B |
title_full | Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B |
title_fullStr | Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B |
title_full_unstemmed | Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B |
title_short | Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B |
title_sort | comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes a and b |
topic | метапневмовирус птиц иммунный ответ экспериментальное заражение avian metapneumovirus immune response experimental inoculation |
url | https://veterinary.arriah.ru/jour/article/view/282 |
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