Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B

After experimental inoculation of broiler chickens with subtype A avian metapneumovirus isolate, mild clinical signs were observed on days 6-14 after inoculation. The infected chickens demonstrated slight increase of T-helpers activity in blood, poor specific antibody response, development of specif...

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Main Authors: P. S. Yaroslavtseva, M. A. Volkova, Z. B. Nikonova, N. S. Mudrak, Ir. A. Chvala
Format: Article
Language:English
Published: Da Vinci Media 2018-04-01
Series:Ветеринария сегодня
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Online Access:https://veterinary.arriah.ru/jour/article/view/282
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author P. S. Yaroslavtseva
M. A. Volkova
Z. B. Nikonova
N. S. Mudrak
Ir. A. Chvala
author_facet P. S. Yaroslavtseva
M. A. Volkova
Z. B. Nikonova
N. S. Mudrak
Ir. A. Chvala
author_sort P. S. Yaroslavtseva
collection DOAJ
description After experimental inoculation of broiler chickens with subtype A avian metapneumovirus isolate, mild clinical signs were observed on days 6-14 after inoculation. The infected chickens demonstrated slight increase of T-helpers activity in blood, poor specific antibody response, development of specific secretory antibodies. Subtype B avian metapneumovirus isolate caused a somewhat more obvious specific clinical signs in chickens compared with subtype A on days 5-15 after inoculation, however, in both experiments, clinical signs completely disappeared in 14-15 days after infection. The increase of relative number of cytotoxic T lymphocytes in blood and in spleen, specific antibody response in 50-70% of chickens and activation of local immune response in 50% of chickens were observed in inoculated chickens.
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institution Kabale University
issn 2304-196X
2658-6959
language English
publishDate 2018-04-01
publisher Da Vinci Media
record_format Article
series Ветеринария сегодня
spelling doaj-art-1726efbbcc674ce19fb36ad59bec57072025-02-06T09:52:06ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592018-04-01011722282Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and BP. S. Yaroslavtseva0M. A. Volkova1Z. B. Nikonova2N. S. Mudrak3Ir. A. Chvala4FGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirAfter experimental inoculation of broiler chickens with subtype A avian metapneumovirus isolate, mild clinical signs were observed on days 6-14 after inoculation. The infected chickens demonstrated slight increase of T-helpers activity in blood, poor specific antibody response, development of specific secretory antibodies. Subtype B avian metapneumovirus isolate caused a somewhat more obvious specific clinical signs in chickens compared with subtype A on days 5-15 after inoculation, however, in both experiments, clinical signs completely disappeared in 14-15 days after infection. The increase of relative number of cytotoxic T lymphocytes in blood and in spleen, specific antibody response in 50-70% of chickens and activation of local immune response in 50% of chickens were observed in inoculated chickens.https://veterinary.arriah.ru/jour/article/view/282метапневмовирус птициммунный ответэкспериментальное заражениеavian metapneumovirusimmune responseexperimental inoculation
spellingShingle P. S. Yaroslavtseva
M. A. Volkova
Z. B. Nikonova
N. S. Mudrak
Ir. A. Chvala
Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B
Ветеринария сегодня
метапневмовирус птиц
иммунный ответ
экспериментальное заражение
avian metapneumovirus
immune response
experimental inoculation
title Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B
title_full Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B
title_fullStr Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B
title_full_unstemmed Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B
title_short Comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes A and B
title_sort comparison of immune response in broiler chickens after experimental inoculation with isolates of avian metapneumovirus subtypes a and b
topic метапневмовирус птиц
иммунный ответ
экспериментальное заражение
avian metapneumovirus
immune response
experimental inoculation
url https://veterinary.arriah.ru/jour/article/view/282
work_keys_str_mv AT psyaroslavtseva comparisonofimmuneresponseinbroilerchickensafterexperimentalinoculationwithisolatesofavianmetapneumovirussubtypesaandb
AT mavolkova comparisonofimmuneresponseinbroilerchickensafterexperimentalinoculationwithisolatesofavianmetapneumovirussubtypesaandb
AT zbnikonova comparisonofimmuneresponseinbroilerchickensafterexperimentalinoculationwithisolatesofavianmetapneumovirussubtypesaandb
AT nsmudrak comparisonofimmuneresponseinbroilerchickensafterexperimentalinoculationwithisolatesofavianmetapneumovirussubtypesaandb
AT irachvala comparisonofimmuneresponseinbroilerchickensafterexperimentalinoculationwithisolatesofavianmetapneumovirussubtypesaandb