Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography

Purpose. To evaluate intraobserver and interobserver agreement in locating the scleral spur landmark (SSL) and anterior chamber angle measurements obtained using Fourier Domain Anterior Segment Optical Coherence Tomography (ASOCT) images. Methods. Two independent, masked observers (SR and AZC) ident...

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Main Authors: Ricardo J. Cumba, Sunita Radhakrishnan, Nicholas P. Bell, Kundandeep S. Nagi, Alice Z. Chuang, Shan C. Lin, Kimberly A. Mankiewicz, Robert M. Feldman
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2012/487309
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author Ricardo J. Cumba
Sunita Radhakrishnan
Nicholas P. Bell
Kundandeep S. Nagi
Alice Z. Chuang
Shan C. Lin
Kimberly A. Mankiewicz
Robert M. Feldman
author_facet Ricardo J. Cumba
Sunita Radhakrishnan
Nicholas P. Bell
Kundandeep S. Nagi
Alice Z. Chuang
Shan C. Lin
Kimberly A. Mankiewicz
Robert M. Feldman
author_sort Ricardo J. Cumba
collection DOAJ
description Purpose. To evaluate intraobserver and interobserver agreement in locating the scleral spur landmark (SSL) and anterior chamber angle measurements obtained using Fourier Domain Anterior Segment Optical Coherence Tomography (ASOCT) images. Methods. Two independent, masked observers (SR and AZC) identified SSLs on ASOCT images from 31 eyes with open and nonopen angles. A third independent reader, NPB, adjudicated SSL placement if identifications differed by more than 80 μm. Nine months later, SR reidentified SSLs. Intraobserver and interobserver agreement in SSL placement, trabecular-iris space area (TISA750), and angle opening distance (AOD750) were calculated. Results. In 84% of quadrants, SR’s SSL placements during 2 sessions were within 80 μm in both the X- and Y-axes, and in 77% of quadrants, SR and AZC were within 80 μm in both axes. In adjudicated images, 90% of all quadrants were within 80 μm, 88% in nonopen-angle eyes, and 92% in open-angle eyes. The intraobserver and interobserver correlation coefficients (with and without adjudication) were above 0.9 for TISA750 and AOD750 for all quadrants. Conclusions. Reproducible identification of the SSL from images obtained with FD-ASOCT is possible. The ability to identify the SSL allows reproducible measurement of the anterior chamber angle using TISA750 and AOD750.
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spelling doaj-art-172123c808f04dfda4b97261efe17eac2025-02-03T07:24:52ZengWileyJournal of Ophthalmology2090-004X2090-00582012-01-01201210.1155/2012/487309487309Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence TomographyRicardo J. Cumba0Sunita Radhakrishnan1Nicholas P. Bell2Kundandeep S. Nagi3Alice Z. Chuang4Shan C. Lin5Kimberly A. Mankiewicz6Robert M. Feldman7Ruiz Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 6431 Fannin Street, MSB 7.024, Houston, TX 77030, USAGlaucoma Center of San Francisco, 55 Stevenson Street, San Francisco, CA 94105, USARuiz Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 6431 Fannin Street, MSB 7.024, Houston, TX 77030, USARuiz Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 6431 Fannin Street, MSB 7.024, Houston, TX 77030, USARuiz Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 6431 Fannin Street, MSB 7.024, Houston, TX 77030, USADepartment of Ophthalmology, University of California, San Francisco, 10 Koret Way, Room K-300, P.O. Box 0730, San Francisco, CA 94143, USARuiz Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 6431 Fannin Street, MSB 7.024, Houston, TX 77030, USARuiz Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 6431 Fannin Street, MSB 7.024, Houston, TX 77030, USAPurpose. To evaluate intraobserver and interobserver agreement in locating the scleral spur landmark (SSL) and anterior chamber angle measurements obtained using Fourier Domain Anterior Segment Optical Coherence Tomography (ASOCT) images. Methods. Two independent, masked observers (SR and AZC) identified SSLs on ASOCT images from 31 eyes with open and nonopen angles. A third independent reader, NPB, adjudicated SSL placement if identifications differed by more than 80 μm. Nine months later, SR reidentified SSLs. Intraobserver and interobserver agreement in SSL placement, trabecular-iris space area (TISA750), and angle opening distance (AOD750) were calculated. Results. In 84% of quadrants, SR’s SSL placements during 2 sessions were within 80 μm in both the X- and Y-axes, and in 77% of quadrants, SR and AZC were within 80 μm in both axes. In adjudicated images, 90% of all quadrants were within 80 μm, 88% in nonopen-angle eyes, and 92% in open-angle eyes. The intraobserver and interobserver correlation coefficients (with and without adjudication) were above 0.9 for TISA750 and AOD750 for all quadrants. Conclusions. Reproducible identification of the SSL from images obtained with FD-ASOCT is possible. The ability to identify the SSL allows reproducible measurement of the anterior chamber angle using TISA750 and AOD750.http://dx.doi.org/10.1155/2012/487309
spellingShingle Ricardo J. Cumba
Sunita Radhakrishnan
Nicholas P. Bell
Kundandeep S. Nagi
Alice Z. Chuang
Shan C. Lin
Kimberly A. Mankiewicz
Robert M. Feldman
Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography
Journal of Ophthalmology
title Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography
title_full Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography
title_fullStr Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography
title_full_unstemmed Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography
title_short Reproducibility of Scleral Spur Identification and Angle Measurements Using Fourier Domain Anterior Segment Optical Coherence Tomography
title_sort reproducibility of scleral spur identification and angle measurements using fourier domain anterior segment optical coherence tomography
url http://dx.doi.org/10.1155/2012/487309
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